Evidence map›Paper›PMID 30976838›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2019

[Decision-making support in Intensive Care to facilitate organ donation : Position paper of the Ethics Section and the Organ Donation and Transplantation Section of the German Interdisciplinary Association of Critical Care and Emergency Medicine (DIVI) in collaboration with the Ethics Section of the German Society of Medical Intensive Care Medicine and Emergency Medicine (DGIIN)].

G Neitzke, A Rogge, K M Lücking, B Böll, H Burchardi, K Dannenberg, G Duttge, J Dutzmann, R Erchinger, P Gretenkort and 14 more

Registry-linked trialAbstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04131140 (Differences Across ICUs in Organ Donation After Brain Death), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04131140 completednot on this map

Differences Across ICUs in Organ Donation After Brain Death: A Nationwide Study of Relationship With Variation in End-of-life Decisions

Typeobservational_patient_registrySponsorSwedish Intensive Care RegistryRan2014 to 2018Enrolled12,072ConditionsDecision Making, Terminal Illness, Tissue and Organ Procurement
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. [Dying in the intensive care unit].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. [Amendments to the Transplantation Act and impact on the donor situation in Germany].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 18 institutions in 1 country.

G NeitzkeInstitut für Geschichte, Ethik und Philosophie der Medizin, Medizinische Hochschule Hannover, Hannover, Deutschland.
A RoggeKlinische Ethikberatung, Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel, Deutschland.
K M LückingUniversitätsklinikum Freiburg, Freiburg, Deutschland.
B BöllKlinik I für Innere Medizin, Uniklinik Köln, Köln, Deutschland.
H Burchardi, Bovenden, Deutschland.
K DannenbergMedizinische Klinik, BG Klinikum Bergmannstrost, Halle, Deutschland.
G DuttgeAbteilung für strafrechtliches Medizin- und Biorecht, Georg-August-Universität Göttingen, Göttingen, Deutschland.
J DutzmannUniversitätsklinik und Poliklinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum Halle (Saale), Halle, Deutschland.
R Erchinger, Schopp, Deutschland.
P GretenkortSimulations- und Notfallakademie, Helios Klinikum Krefeld, Krefeld, Deutschland.
C HartogPatienten- und Angehörigenzentrierte Versorgung, Klinik Bavaria Kreischa, Kreischa, Deutschland.
S JöbgesKlinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin, Campus Charité Mitte und Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
K KnochelKinderpalliativzentrum München, Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital, Klinikum der Universität München, München, Deutschland.
M LiebigMedizinische Klinik, Klinikum Görlitz, Görlitz, Deutschland.
S MeierKlinik für Anästhesiologie, Universitätsklinikum Düsseldorf, Düsseldorf, Deutschland.
A MichalsenKlinik für Anästhesiologie, Intensivmedizin, Notfallmedizin und Schmerztherapie, Klinik Tettnang, Tettnang, Deutschland.
G MichelsKlinik III für Innere Medizin, Uniklinik Köln, Köln, Deutschland.
M MohrKlinik für Anästhesiologie und Intensivmedizin, Ev. Diakonie-Krankenhaus, Bremen, Deutschland.
F NauckKlinik für Palliativmedizin, Universitätsmedizin Göttingen, Göttingen, Deutschland.
F Salomon, Lemgo, Deutschland.
A-H SeidleinInstitut für Ethik und Geschichte in der Medizin, Universitätsmedizin Greifswald, Greifswald, Deutschland.
G SöffkerZentrum für Intensivmedizin, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
H Stopfkuchen, Mainz, Deutschland.
U JanssensKlinik für Innere Medizin und Internistische Intensivmedizin, St.-Antonius-Hospital, Dechant-Deckers-Str. 8, 52249, Eschweiler, Deutschland. uwe.janssens@sah-eschweiler.de.
University Hospital Cologne · DEBG Klinikum Bergmannstrost Halle · DECharité - Universitätsmedizin Berlin · DEDüsseldorf University Hospital · DEHelios Klinikum Krefeld · DEKlinik Bavaria · DEKlinikum Görlitz · DELMU Klinikum · DEMedizinische Hochschule Hannover · DESankt-Antonius-Hospital Eschweiler · DEUniversität Hamburg · DEUniversitäts Hautklinik Kiel · DEUniversitätsmedizin Göttingen · DEUniversitätsmedizin Greifswald · DEUniversity Hospital in Halle · DEUniversity Medical Center Freiburg · DEUniversity of Applied Sciences Mainz · DEUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and challengeInjuries, especially traumatic brain injury, or specific illnesses and their respective sequelae can result in the demise of the patients afflicted despite all efforts of modern intensive care medicine. If in principle organ donation is an option after a patient's death, intensive therapeutic measures are regularly required in order to maintain the homeostasis of the organs. These measures, however, cannot benefit the patient afflicted anymore-which in turn might lead to an ethical conflict between dignified palliative care for him/her and expanded intensive treatment to facilitate organ donation for others, especially if the patient has opted for the limitation of life-sustaining therapies in an advance directive.

methodThe Ethics Section and the Organ Donation and Transplantation Section of the German Interdisciplinary Association of Critical Care and Emergency Medicine (DIVI) have convened several meetings and a telephone conference and have arrived at a decision-making aid as to the extent of treatment for potential organ donors. This instrument focusses first on the assessment of five individual dimensions regarding organ donation, namely the certitude of a complete and irreversible loss of all brain function, the patient's wishes as to organ donation, his or her wishes as to limiting life-sustaining therapies, the intensity of expanded intensive treatment for organ protection and the odds of its successful attainment. Then, the combination of the individual assessments, as graphically shown in a {Netzdiagramm}, will allow for a judgement as to whether a continuation or possibly an expansion of intensive care measures is ethically justified, questionable or even inappropriate.

resultThe aid described can help mitigate ethical conflicts as to the extent of intensive care treatment for moribund patients, when organ donation is a medically sound option. NOTE: Gerald Neitzke und Annette Rogge contributed equally to this paper and should be considered co-first authors.

Indexed as

Decision MakingEmergency MedicineOrgan TransplantationTissue and Organ ProcurementCritical CareHumansTissue DonorsEnd-of-life careExtent of intensive care treatmentIntensive care medicineOrgan donationOrgan transplantation

Identifiers

PMID30976838
OpenAlexW2939094878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.