Evidence map›Paper›PMID 30976671›Full record

ArticleHeliyon2019

Naturally occurring sesquiterpene lactones and their semi-synthetic derivatives modulate PGE2 levels by decreasing COX2 activity and expression.

Filomena Perri, Luca Frattaruolo, Ian Haworth, Matteo Brindisi, Asma El-magboub, Angela Ferrario, Charles Gomer, Francesca Aiello, James David Adams

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Modulation of the PGEMolecules (Basel, Switzerland) · 2021
    Article
  6. Article
  7. Research Advances on Health Effects of EdibleFoods (Basel, Switzerland) · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Filomena PerriDipartimento di Farmacia e Scienze della Salute e della Nutrizione, Edificio Polifunzionale, Università della Calabria, Arcavacata di Rende, 87036 Rende (CS), Italy.
Luca FrattaruoloDipartimento di Farmacia e Scienze della Salute e della Nutrizione, Edificio Polifunzionale, Università della Calabria, Arcavacata di Rende, 87036 Rende (CS), Italy.
Ian HaworthDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Sothern California, 1985 Zonal Avenue, Los Angeles 90089, CA, USA.
Matteo BrindisiDipartimento di Farmacia e Scienze della Salute e della Nutrizione, Edificio Polifunzionale, Università della Calabria, Arcavacata di Rende, 87036 Rende (CS), Italy.
Asma El-magboubDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Sothern California, 1985 Zonal Avenue, Los Angeles 90089, CA, USA.
Angela FerrarioChildren's Hospital Los Angeles, University of Southern California, 4650 W Sunset Boulevard, Los Angeles 90027, CA, USA.
Charles GomerChildren's Hospital Los Angeles, University of Southern California, 4650 W Sunset Boulevard, Los Angeles 90027, CA, USA.
Francesca AielloDipartimento di Farmacia e Scienze della Salute e della Nutrizione, Edificio Polifunzionale, Università della Calabria, Arcavacata di Rende, 87036 Rende (CS), Italy.
James David AdamsDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Sothern California, 1985 Zonal Avenue, Los Angeles 90089, CA, USA.
University of Calabria · ITChildren's Hospital of Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants of the Asteraceae family have been used in traditional medicine for centuries due to their main antimicrobial and analgesic activities. A liniment from

Indexed as

Natural product chemistryOrganic chemistryPharmaceutical chemistry

Identifiers

PMID30976671
PMCPMC6441754
OpenAlexW2931101736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.