ArticleInternational journal of cardiology. Heart & vasculature2019
Risks of age and sex on clinical outcomes post myocardial infarction.
Article in International journal of cardiology. Heart & vasculature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Factors affecting hospital readmission rates following an acute coronary syndrome: A systematic review.Journal of clinical nursing · 2022Pooled it
- Evolocumab early reduces IL-1β/IL-17A and improves left ventricular function in STEMI: an observational study in the real world.Frontiers in pharmacology · 2026Article
- Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularization.The Journal of international medical research · 2024Article
- The Relationship between Erectile Dysfunction, Self-Esteem, and Depression in Post-Myocardial Infarction Patients.Journal of clinical medicine · 2024Article
- Impact of Sex in the Incidence of Heart Failure in Patients with Chronic Coronary Syndrome.Current heart failure reports · 2024Review
- Sex Differences in Ventricular Arrhythmias and Adverse Outcomes Following Acute Myocardial Infarction.JACC. Advances · 2024Article
- Kharameh cohort study (KHCS) on non-communicable diseases and preliminary findings of 3-year follow-up.BMJ open · 2024Article
- Predictive factors of heart failure in acute coronary syndrome: Institutional cross-sectional study.Annals of medicine and surgery (2012) · 2022Article
- Automatic Multichannel Electrocardiogram Record Classification Using XGBoost Fusion Model.Frontiers in physiology · 2022Article
- Heart failure after myocardial infarction: incidence and predictors.ESC heart failure · 2021Review
- Gender differences in clinical outcomes of acute myocardial infarction undergoing percutaneous coronary intervention: insights from the KAMIR-NIH Registry.Journal of geriatric cardiology : JGC · 2020Article
- Highlights from the International Journal of Cardiology Heart & Vasculature: Heart failure, atrial fibrillation, coronary artery disease and myocardial infarction.International journal of cardiology. Heart & vasculature · 2019Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHow sex and age influence post-myocardial infarction (post-MI) outcomes remains unclear. This study evaluated the influence of sex and age on drug therapy, echocardiographic parameters, and outcomes in post-MI patients undergoing percutaneous coronary intervention (PCI).
methodsWe retrospectively enrolled 643 patients with first acute MI who underwent successful PCI and two echocardiographic examinations within 1 year after MI. Clinical characteristics and 4-year follow-up outcomes were compared between sexes and age groups. Primary endpoints were cardiovascular mortality and hospitalization for heart failure (HF).
resultsCompared with males, female patients with MI, particularly older females, had more systemic diseases. Younger females received fewer guideline-directed therapies. Older patients presented with higher left ventricular volume and mass index but no significant differences in left ventricular ejection fraction. The Kaplan-Meier analysis revealed increased mortality in both younger and older females. Elderly patients, particularly older females, exhibited significantly higher post-MI HF incidence but no difference in recurrent MI, ventricular arrhythmia, or revascularization.
conclusionsIn MI patients receiving PCI, outcome differences between sexes are age-dependent. Age influences outcome more heavily in females than in males. Females are likely to exhibit worse overall survival, and older females are at higher risk of post-MI HF.
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