Diagnostic performance of 2015 American Thyroid Association guidelines and inter-observer variability in assigning risk category.

Zhiyu Pang, Myles Margolis, Ravi J Menezes, Hassaan Maan, Sangeet Ghai

Erratum issuedAbstract read

In one paragraph

Article in European journal of radiology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

8citing papers in PubMed, 1 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

Malignancy Risk of Thyroid Nodules That Are Not Classifiable by the American Thyroid Association Ultrasound Risk Stratification System: A Systematic Review and Meta-Analysis.Thyroid : official journal of the American Thyroid Association · 2023
Pooled it
Considerable interobserver variation calls for unambiguous definitions of thyroid nodule ultrasound characteristics.European thyroid journal · 2023
Article
Clinician Agreement on the Classification of Thyroid Nodules Ultrasound Features: A Survey of 2 Endocrine Societies.The Journal of clinical endocrinology and metabolism · 2022
Article
Summary of Meta-analyses of Studies Considering Lesion Size Cut-off Thresholds for The Assessment of Eligibility for FNAB and Sonoelastography and Inter- and Intra-observer Agreement in Estimating the Malignant Potential of Focal Lesions of The Thyroid Gland.Journal of ultrasonography · 2022
Article
Thyroid Nodule Size as a Predictor of Malignancy in Follicular and Hurthle Neoplasms.Asian Pacific journal of cancer prevention : APJCP · 2021
Article
A Preliminary Study of Quantitative Ultrasound for Cancer-Risk Assessment of Thyroid Nodules.Frontiers in endocrinology · 2021
Article
Interobserver variability in quality assessment of magnetic resonance images.BMC medical imaging · 2020
Article
Classification and Regression Tree (CART) model of sonographic signs in predicting thyroid nodules malignancy.European journal of radiology open · 2019
Article

4 · The record

Corrections and comments

Erratum issued
Erratum regarding missing Declaration of Competing Interest statements in previously published articles.2021

5 · Who and what money

Authors and funding

5 authors.

Zhiyu PangToronto Joint Department of Medical Imaging, University Health Network - Mount Sinai Hospital - Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Myles MargolisToronto Joint Department of Medical Imaging, University Health Network - Mount Sinai Hospital - Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Ravi J MenezesToronto Joint Department of Medical Imaging, University Health Network - Mount Sinai Hospital - Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Hassaan MaanToronto Joint Department of Medical Imaging, University Health Network - Mount Sinai Hospital - Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Sangeet GhaiToronto Joint Department of Medical Imaging, University Health Network - Mount Sinai Hospital - Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the interobserver variability of the 2015 American Thyroid Association (ATA) thyroid guidelines and to evaluate the diagnostic accuracy of the guidelines in detecting thyroid cancer. MATERIALS AND

methodsSonographic patterns of 189 thyroid lesions were retrospectively analyzed by two radiologists according to the 2015 guidelines. The risk of malignancy was calculated for each pattern and compared with the published expected risk of malignancy.

resultsThe observed risk of malignancy for very low suspicion, low suspicion, intermediate suspicion and high suspicion patterns were 2%, 12.7%, 26.3% and 29.8% respectively. Interobserver agreement for final category assignment was moderate (κ 0.518).

conclusionThe estimated risk of malignancy in the high suspicion pattern of the 2015 ATA thyroid biopsy guidelines appears to be less than stated. However, this needs further validation in a larger cohort study.

Indexed as

ATA guidelinesFine needle aspiration biopsyInterobserver agreementInterobserver variabilityThyroid ultrasound

Identifiers

PMID30976628

DOI10.1016/j.ejro.2019.03.002

PMCPMC6443900

What OpenQuestion holds

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LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.