Evidence map›Paper›PMID 30976593›Full record

ArticleOcular oncology and pathology2019

Metastatic Cutaneous Melanoma Presenting with Choroidal Metastasis Simulating Primary Uveal Melanoma.

Lesley Everett, Bertil E Damato, Michele M Bloomer, James D Palmer, Andrew A Kao, Jay M Stewart, Armin R Afshar

Open access · bronzeAbstract read
In one paragraph

Article in Ocular oncology and pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lesley EverettDepartment of Ophthalmology, University of California, San Francisco, California, USA.
Bertil E DamatoDepartment of Ophthalmology, University of California, San Francisco, California, USA.
Michele M BloomerDepartment of Ophthalmology, University of California, San Francisco, California, USA.
James D PalmerNorthern California Retina-Vitreous Associates, Mountain View, California, USA.
Andrew A KaoDepartment of Ophthalmology, University of California, San Francisco, California, USA.
Jay M StewartDepartment of Ophthalmology, University of California, San Francisco, California, USA.
Armin R AfsharDepartment of Ophthalmology, University of California, San Francisco, California, USA.
University of California, San Francisco · USRetina Vitreous Associates of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a case of metastatic cutaneous melanoma presenting with choroidal metastasis simulating primary uveal melanoma.

designCase report.

methodPresentation of clinical, radiographic, histopathologic, and tumor genetic findings in a patient with cutaneous melanoma with choroidal metastasis.

resultsA 50-year-old man with a remote history of stage 1A cutaneous melanoma presented with eye pain, peripheral vision loss, floaters, red eye, and choroidal mass that was originally diagnosed as a primary uveal melanoma at an outside institution; however, subsequent imaging and clinical evaluation demonstrated that this choroidal mass was the first manifestation of widely metastatic cutaneous melanoma (liver, pancreas, lung, bone, brain, and orbit lesions). Histopathologic analysis of the tumor after enucleation was consistent with cutaneous melanoma, and tumor genetic testing was positive for

conclusionsMetastatic cutaneous melanoma to the orbit or globe occurs rarely. Tumor genetic testing may help differentiate metastatic cutaneous melanoma from primary uveal melanoma in cases where the diagnosis is uncertain, and can also inform therapy and prognostic counseling.

Indexed as

Genetic testingMetastatic cutaneous melanomaOcular metastasis

Identifiers

PMID30976593
PMCPMC6422132
OpenAlexW2887386414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.