Evidence map›Paper›PMID 30976554›Full record

ArticleQuantitative imaging in medicine and surgery2019

Left ventricular longitudinal strain is associated with mitral annular fractional area change in healthy subjects-Results from the three-dimensional speckle tracking echocardiographic MAGYAR-Healthy Study.

Zsolt Kovács, Árpád Kormányos, Péter Domsik, Anita Kalapos, Csaba Lengyel, Nóra Ambrus, Zénó Ajtay, Györgyike Á Piros, Tamás Forster, Attila Nemes

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Article in Quantitative imaging in medicine and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

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9citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Zsolt KovácsDepartment of Cardiology, Szent Rókus Hospital, Baja, Hungary.
Árpád Kormányos2nd Department of Medicine and Cardiology Centre.
Péter Domsik2nd Department of Medicine and Cardiology Centre.
Anita Kalapos2nd Department of Medicine and Cardiology Centre.
Csaba Lengyel1st Department of Medicine, Medical Faculty, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary.
Nóra Ambrus2nd Department of Medicine and Cardiology Centre.
Zénó AjtayVilmos Zsigmondy SPA Hospital, Harkány, Hungary.
Györgyike Á Piros2nd Department of Medicine and Cardiology Centre.
Tamás Forster2nd Department of Medicine and Cardiology Centre.
Attila Nemes2nd Department of Medicine and Cardiology Centre.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe mitral annulus (MA) plays a significant role in promoting left atrial and left ventricular (LV) filling and emptying, which is dependent on LV functional properties. The present study aimed to investigate the relationship between LV strains, quantitative features of longitudinal contractility and MA size and function in healthy subjects.

methodsThe present study comprised 295 healthy adults; 117 subjects were excluded due to inferior image quality (40%). Finally, 178 healthy adults (mean age: 32.0±11.3 years, 92 males). Complete two-dimensional Doppler echocardiography and three-dimensional speckle-tracking echocardiography were performed in all cases.

resultsThe global and mean segmental left ventricular longitudinal strain (LV-LS) proved to be -16.1%±2.5% and -16.9%±2.4%, respectively. In the present study, LV-LS ≤-13% was considered to be reduced. In ROC analysis, the cut-off value for MA fractional area change (MAFAC) to predict impaired LV-LS was ≤44%, with 67% sensitivity and 69% specificity and ROC area under curve 0.73 (P=0.0005). Significantly increased LV volumes and LV mass and reduced MAFAC could be demonstrated in healthy subjects with global LV-LS ≤-13%. Significantly larger ratio of subjects with global LV-LS ≤-13% had MAFAC ≤44% (31%

conclusionsThere is a strong relationship between MA and LV longitudinal function. MA fractional area change predicts global LV-LS.

Indexed as

echocardiographyHealthyleft ventricular (LV)mitral annulus (MA)speckle-trackingstrainthree-dimensional

Identifiers

PMID30976554
PMCPMC6414771

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.