Evidence map›Paper›PMID 30976539›Full record

ArticleQuantitative imaging in medicine and surgery2019

Circumferential strain rate to detect lipopolysaccharide-induced cardiac dysfunction: a speckle tracking echocardiography study.

Ming Chu, Lijun Qian, Menglin Zhu, Jing Yao, Di Xu, Minglong Chen

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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  5. [Protective effect of excretory-secretory proteins fromNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ming ChuDepartment of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Lijun QianDepartment of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Menglin ZhuDepartment of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Jing YaoDepartment of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Di XuDepartment of Geriatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Minglong ChenDepartment of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Jiangsu Province Hospital · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLipopolysaccharide (LPS)-induced myocardial dysfunction is a widely used indicator to study septic cardiomyopathy (SC). This study investigated the efficiency of strain rate imaging (SRI) in detecting LPS-induced myocardial dysfunction.

methodsA total of 30 mice were randomly assigned to saline group (n=10), 10 mg/kg LPS group (n=10) and 20 mg/kg LPS group (n=10). Then at baseline, 6 and 20 h after LPS injection, 2-D and M-mode echocardiography were conducted with GE Vivid 7 ultrasound (il3L linear probe, 10.0-14.0 MHz) and Echopac PC software. Ejection fraction (EF) and fractional shortening (FS) were measured with M-mode tracings. Serum biochemical examination was then performed to evaluate sepsis-induced myocardial injury.

resultsIn LPS 20 mg/kg group, at 6 h after LPS injection, SRI found significantly decreased early diastolic strain rate (SRe, 1.76±1.05

conclusionsSRI is useful to early assess LPS-induced cardiac deformation in mice. circumferential strain rate (SRcirc) is a sensitive indicator for LPS-induced myocardial injury in severe sepsis.

Indexed as

circumferential strain rate (SRcirc)lipopolysaccharide (LPS)Septic cardiomyopathy (SC)speckle tracking echocardiography (STE)strain rate imaging (SRI)

Identifiers

PMID30976539
PMCPMC6414778
OpenAlexW2900935554

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.