Surgical technique for developing a rabbit model of congenital diaphragmatic hernia and tracheal occlusion.

M Mudri, S A Smith, C Vander Tuin, J Davidson, T R H Regnault, A Bütter

Open access · goldAbstract read

In one paragraph

Article in MethodsX, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 96% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

M MudriDivision of General Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

S A SmithDivision of General Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

C Vander TuinDepartments of Obstetrics & Gynaecology and Physiology & Pharmacology, Schulich School of Medicine, Western University, London, ON, Canada.

J DavidsonDivision of Paediatric General Surgery, Children's Hospital London Health Science Centre, Schulich School of Medicine, Western University, London, ON, Canada.

T R H RegnaultDepartments of Obstetrics & Gynaecology and Physiology & Pharmacology, Schulich School of Medicine, Western University, London, ON, Canada.

A BütterDivision of Paediatric General Surgery, Children's Hospital London Health Science Centre, Schulich School of Medicine, Western University, London, ON, Canada.

Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The surgical model of congenital diaphragmatic hernia (CDH) has been utilized in exploring treatments and innovative therapies, such as tracheal occlusion (TO). The rabbit is an excellent surgical model compared to others due to lower cost, ease of care, short gestational period, and large litter size. This model is also ideal in studying lung hypoplasia of CDH because rabbit lung development is most similar to humans as alveolarization begins prior to birth and continues post-natally. However, the surgical technique in creating a rabbit model of CDH is quite difficult and information is lacking on how to establish this model. Therefore, the aim of this paper is to describe: •Surgical technique in establishing a rabbit model of CDH and TO•Perioperative care for pregnant rabbit does.

Indexed as

Animal modelCongenital diaphragmatic hernia (CDH)Fetal surgeryRabbitRabbit model of congenital diaphragmatic hernia and tracheal occlusionTracheal occlusion (TO)

Identifiers

PMID30976533

DOI10.1016/j.mex.2019.03.001

PMCPMC6441759

OpenAlexW2922712241

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.