Evidence map›Paper›PMID 30976402›Full record

ArticleClinical kidney journal2019

Membranous nephropathy due to chronic mercury poisoning from traditional Indian medicines: report of five cases.

Manan Doshi, Rajeev A Annigeri, Prakash C Kowdle, Budithi Subba Rao, Mahendran Varman

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

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  13. Mercury in natural health products as a cause of membranous nephropathy.Proceedings (Baylor University. Medical Center) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Manan DoshiDepartment of Nephrology, Apollo Hospitals, Chennai, Tamil Nadu, India.
Rajeev A AnnigeriDepartment of Nephrology, Apollo Hospitals, Chennai, Tamil Nadu, India.ORCID 0000-0001-5282-3592
Prakash C KowdleDepartment of Nephrology, Apollo Hospitals, Chennai, Tamil Nadu, India.
Budithi Subba RaoDepartment of Nephrology, Apollo Hospitals, Chennai, Tamil Nadu, India.
Mahendran VarmanDepartment of Nephrology, Apollo Hospitals, Chennai, Tamil Nadu, India.
Apollo Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mercury contained in traditional medicines can cause chronic poisoning, which can cause membranous nephropathy (MN). We report five cases of nephrotic syndrome caused by MN with evidence of chronic mercury poisoning due to consumption of traditional Indian medicines such as Siddha and Ayurveda, which to our knowledge are the first such reports. All patients were seronegative for antibodies against phospholipase A2 receptor (PLA2R). Two patients, who had severe nephrotic syndrome, had received Siddha medicine for prolonged period and oral chelation with dimercaptopropane-1-sulfonic acid was successful in eliminating mercury, resulting in an improvement in nephrotic state in these patients. We suggest that mercury poisoning should be entertained in patients with anti-PLA2R antibody-negative MN, with history of consumption of traditional Indian medicines.

Indexed as

dimercaptopropane-1-sulfonic acidmembranous nephropathymercurynephrotic syndrometraditional Indian medicine

Identifiers

PMID30976402
PMCPMC6452196
OpenAlexW2805937660

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.