Evidence map›Paper›PMID 30976162›Full record

ArticleJournal of ginseng research2019

Developmental and reproductive toxicity assessment in rats with KGC-HJ3, Korean Red Ginseng with

Jinsoo Lee, Ji-Seong Jeong, Kyung-Jin Cho, Kyeong-Nang Moon, Sang Yun Kim, Byungcheol Han, Yong-Soon Kim, Eun Ju Jeong, Moon-Koo Chung, Wook-Joon Yu

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Reproductive Toxicity ofJournal of toxicology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jinsoo LeeDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Ji-Seong JeongDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Kyung-Jin ChoDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Kyeong-Nang MoonDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Sang Yun KimDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Byungcheol HanFundamental Laboratory, R&D Headquarters, Korea Ginseng Corp., Daejeon, Republic of Korea.
Yong-Soon KimChronic Inhalation Toxicity Research Center, Chemicals Toxicity Research Bureau, Occupational Safety and Health Research Institute, KOSHA, Daejeon, Republic of Korea.
Eun Ju JeongDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Moon-Koo ChungDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Wook-Joon YuDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Korea Institute of Toxicology · KRKorean Society of Ginseng · KRKorea Occupational Safety and Health Agency · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKorean Red Ginseng has been widely used in traditional oriental medicine for a prolonged period, and its pharmacological effects have been extensively investigated. In addition,

methodsThis study was conducted to evaluate the potential toxicological effect of KGC-HJ3, Korean Red Ginseng with RESULTS AND

conclusionNo test item-related changes in parameters for fertility, early embryonic development, maternal function, and embryo-fetal development were observed during the study period. On the basis of these results, it was concluded that KGC-HJ3 did not have toxicological potential on developmental and reproductive functions. Therefore, no observed adverse effect levels of KGC-HJ3 for fertility, early embryonic development, maternal function, and embryo-fetal development is considered to be at least 2000 mg/kg/day.

Indexed as

Angelica gigasDeer antlersDevelopmental and reproductive toxicologyKGC-HJ3Korean Red Ginseng

Identifiers

PMID30976162
PMCPMC6437469
OpenAlexW2783326311

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.