Evidence map›Paper›PMID 30976133›Full record

ArticlePolyhedron2019

Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads.

Timothy J Hubin, Ashlie N Walker, Dustin J Davilla, TaRynn N Carder Freeman, Brittany M Epley, Travis R Hasley, Prince N A Amoyaw, Surendra Jain, Stephen J Archibald, Timothy J Prior and 4 more

Open access · greenAbstract read
In one paragraph

Article in Polyhedron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Antifouling Properties ofMolecules (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Disclosing the Antifungal Mechanisms of the Cyclam Salt HInternational journal of molecular sciences · 2024
    Article
  4. A Cyclam Salt as an Antifungal Agent: Interference withAntibiotics (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Timothy J HubinDepartment of Chemistry and Physics, Southwestern Oklahoma State University. 100 Campus Drive, Weatherford, OK 73096.
Ashlie N WalkerDepartment of Chemistry and Physics, Southwestern Oklahoma State University. 100 Campus Drive, Weatherford, OK 73096.
Dustin J DavillaDepartment of Chemistry and Physics, Southwestern Oklahoma State University. 100 Campus Drive, Weatherford, OK 73096.
TaRynn N Carder FreemanDepartment of Chemistry and Physics, Southwestern Oklahoma State University. 100 Campus Drive, Weatherford, OK 73096.
Brittany M EpleyDepartment of Chemistry and Physics, Southwestern Oklahoma State University. 100 Campus Drive, Weatherford, OK 73096.
Travis R HasleyDepartment of Chemistry and Physics, Southwestern Oklahoma State University. 100 Campus Drive, Weatherford, OK 73096.
Prince N A AmoyawDepartment of Pharmaceutical Sciences, College of Pharmacy, Southwestern Oklahoma State University. 100 Campus Drive, Weatherford, Ok 73096.
Surendra JainNational Center for Natural Products Research and Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, University, MS 38677.
Stephen J ArchibaldDepartment of Chemistry, University of Hull, Cottingham Road, Hull, HU6 7RX.
Timothy J PriorDepartment of Chemistry, University of Hull, Cottingham Road, Hull, HU6 7RX.
Jeanette A KrauseDepartment of Chemistry, University of Cincinnati, 301 Clifton Ct., Cincinnati, OH 45221-0172.
Allen G OliverDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.
Babu L TekwaniNational Center for Natural Products Research and Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, University, MS 38677.
M Omar F KhanDepartment of Pharmaceutical Sciences, College of Pharmacy, Southwestern Oklahoma State University. 100 Campus Drive, Weatherford, Ok 73096.
Southwestern Oklahoma State University · USUniversity of Hull · GBSouthern Research Institute · USUniversity of Cincinnati · USUniversity of Mississippi · USUniversity of Notre Dame · US

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Mark L Lang · 2012 to 2026
$60.2M
NIGMS NIH HHS P20 GM103447
6 · The paper itself

Abstract

A total of 44 bis-aryl-monocyclic polyamines, monoaryl-monocyclic polyamines and their transition metal complexes were prepared, chemically characterized, and screened in vitro against the

Indexed as

antileishmanial drug leadcyclamCyclenmetal complexespolyamine

Identifiers

PMID30976133
PMCPMC6452907
OpenAlexW2917242895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.