Evidence map›Paper›PMID 30976093›Full record

ArticleScientific reports2019

Determination of oligomerization state of Drp1 protein in living cells at nanomolar concentrations.

Karina Kwapiszewska, Tomasz Kalwarczyk, Bernadeta Michalska, Krzysztof Szczepański, Jędrzej Szymański, Paulina Patalas-Krawczyk, Tomasz Andryszewski, Michalina Iwan, Jerzy Duszyński, Robert Hołyst

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Living Cell as a Self-Synchronized Chemical Reactor.The journal of physical chemistry letters · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. NovelLife science alliance · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. In-cell destabilization of a homodimeric protein complex detected by DEER spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Nanoscale Viscosity of Cytoplasm Is Conserved in Human Cell Lines.The journal of physical chemistry letters · 2020
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Karina KwapiszewskaInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland. karina.kwapiszewska@gmail.com.ORCID http://orcid.org/0000-0002-7396-9571
Tomasz KalwarczykInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland.
Bernadeta MichalskaNencki Institute of Experimental Biology, 3 Pasteur St, 02-093, Warsaw, Poland.
Krzysztof SzczepańskiInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland.
Jędrzej SzymańskiNencki Institute of Experimental Biology, 3 Pasteur St, 02-093, Warsaw, Poland.ORCID http://orcid.org/0000-0002-4060-0196
Paulina Patalas-KrawczykNencki Institute of Experimental Biology, 3 Pasteur St, 02-093, Warsaw, Poland.
Tomasz AndryszewskiInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland.
Michalina IwanInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland.
Jerzy DuszyńskiNencki Institute of Experimental Biology, 3 Pasteur St, 02-093, Warsaw, Poland.
Robert HołystInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland. robert.holyst@gmail.com.
Institute of Physical Chemistry · PLInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biochemistry in living cells is an emerging field of science. Current quantitative bioassays are performed ex vivo, thus equilibrium constants and reaction rates of reactions occurring in human cells are still unknown. To address this issue, we present a non-invasive method to quantitatively characterize interactions (equilibrium constants, K

Indexed as

Protein MultimerizationCytosolDynaminsHumansMitochondriaMitochondrial DynamicsMitochondrial MembranesModels, MolecularMutationProtein BindingProtein ConformationProtein TransportDNM1L protein, humanDynamins

Identifiers

PMID30976093
PMCPMC6459820
OpenAlexW2937354681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.