ArticleScientific reports2019
Extent of Resection in Meningioma: Predictive Factors and Clinical Implications.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Improvement in visual outcomes of patients with base of skull meningioma as a result of evolution in the treatment techniques in the last three decades: a systematic review.Journal of neuro-oncology · 2023Pooled it
- Methodological conduct of prognostic prediction models developed using machine learning in oncology: a systematic review.BMC medical research methodology · 2022Pooled it
- Foramen magnum meningiomas: a systematic review and meta-analysis.Neurosurgical review · 2021Pooled it
- Resection of Olfactory Groove Meningiomas Through Unilateral vs. Bilateral Approaches: A Systematic Review and Meta-Analysis.Frontiers in oncology · 2020Pooled it
- Bone Tumor Microenvironment Is Associated with Meningioma Enlargement and Inflammatory Transcriptional States: A Candidate Role for Macrophage-Derived IL-1β.Biomedicines · 2026Article
- Derivation of a data-driven follow-up protocol for resected skull base meningiomas: a Bayesian analysis.Journal of neuro-oncology · 2026Article
- Long-term outcomes following primary resection of intraosseous meningiomas with concurrent cranioplasty: a population-based Swedish multicentre study.Acta neurochirurgica · 2026Article
- From intraosseous meningioma and ossified metaplastic meningioma to osteomeningioma: a novel voxel-based, atlas-normalized MRI framework for the radiological classification of skull-involving meningiomas.Neuroimage. Reports · 2026Article
- FEBAIR microsurgical principles in meningiomas and recurrence: a long-term follow-up series.Frontiers in oncology · 2026Article
- Evolving Treatment Paradigms of Meningiomas; a Precision Medicine Perspective.Current neurology and neuroscience reports · 2025Review
- Management of skull base meningiomas with extracranial extension: resection, recurrence, and prognostic factors.Journal of neuro-oncology · 2025Article
- Recurrence of Resected Skull Base Meningiomas during Long-term Follow-up: Incidence and Predisposing Factors.Journal of neurological surgery. Part B, Skull base · 2025Article
- Giant Meningiomas Invading the Cavernous Sinus: The "Inevitable Ones".Journal of neurological surgery. Part B, Skull base · 2025Article
- Primary Extradural Meningioma: A Systematic Review of Diagnostic Features, Clinical Management, and Surgical Outcomes.Cancers · 2024Review
- Analysis of the Predictability of Postoperative Meningioma Resection Status Based on Clinical Features.Cancers · 2024Article
- Molecular classification to refine surgical and radiotherapeutic decision-making in meningioma.Nature medicine · 2024Article
- Article
- Staged Resection of Difficult-to-Treat Intracranial Meningiomas: A Systematic Review of the Indications, Surgical Approaches, and Postoperative Outcomes.Journal of neurological surgery. Part B, Skull base · 2024Article
- Simpson's Grading Scale for WHO Grade I Meningioma Resection in the Modern Neurosurgical Era: Are We Really Asking the Right Question?Journal of neurological surgery. Part B, Skull base · 2024Article
- Intracranial meningiomas at a tertiary hospital: Spectrum of MRI findings with histopathologic correlation.SA journal of radiology · 2024Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meningiomas present as intracranial extra-axial lesions with dural attachment, which are primarily managed surgically. The extent of resection (EOR) may vary depending on patient- and tumor-related factors. The aim of this study is to identify preoperative predictive factors of EOR and to propose an estimation of the predicted gross total resection (GTR) based of patient- and tumor-characteristics. 1469 patients from a retrospectively (1990 to 2002) and prospectively managed (2003 to 2010) databank of Oslo University Hospital, Norway, totalling 11,414 patient-years of follow-up were included. Patients had a mean age at surgery of 64 ± 20.1 years with a female-to-male ratio was 2.4:1 and a mean KPS of 81.2 ± 12.1. Skull-base meningiomas represented 47% of all cases. WHO grades were I in 92.3%, II in 5.2%, and III in 2.2%. Bone infiltration was described in 18.7% of cases. 39.3% of patients had Simpson I resection, 34.3% had Simpson II, 5.4% had Simpson III, 20.6% had Simpson IV, and 0.5% had Simpson V. The risk factors for incomplete resection were: symptomatic presentation (OR 0.56 [0.43-0.72]), skull-base location (OR 0.79 [0.70-0.88]), and bone invasion (OR 0.85 [0.73-0.99]). Using a recursive partitioning analysis, we propose a classification-tree for the prediction of GTR rate based on preoperatively determinable patient- and tumor characteristics. The identification of preoperative predictors of poor GTR rate may aid clinicians managing meningioma patients. In selected cases were the predicted GTR rate is low, staged treatment with surgical debulking followed by adjuvant therapy may be favored in order to minimize postoperative morbidity and mortality.
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