ArticleScientific reports2019
Endoluminal radiofrequency ablation of the main pancreatic duct is a secure and effective method to produce pancreatic atrophy and to achieve stump closure.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07687901 (Safety and Feasibility of Radiofrequency-Assisted Robotic Distal Pancreatectomy), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Feasibility of Radiofrequency-Assisted Robotic Distal Pancreatectomy (Attachable Coolingbis®)
Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Radiofrequency-based stump management and ductal ablation in robotic central pancreatectomy: a technical note and initial experience.Updates in surgery · 2026Article
- Preclinical trial results of main pancreatic duct endoluminal radiofrequency ablation to reduce postoperative pancreatic fistula.Surgical endoscopy · 2026Article
- Clinical feasibility analysis of reducing the incidence of pancreatic fistula after laparoscopic distal pancreatectomy by using a pancreatic duct stent to occlude the residual main pancreatic duct.Surgical endoscopy · 2026Article
- Endoluminal radiofrequency ablation versus glue for preventing pancreatic fistula: a preclinical protocol study.Updates in surgery · 2026Article
- A 27-Year-Old Man with Chronic Traumatic Pancreatic Fistula Managed with Percutaneous Microwave Ablation.The American journal of case reports · 2025Article
- Optimal reproduction of a porcine benign biliary stricture model using endobiliary radiofrequency ablation.Scientific reports · 2022Article
- Selective use of pancreatic duct occlusion during pancreaticoduodenectomy in patients with a small-size duct and atrophic parenchyma in the distal pancreas: A retrospective study.Frontiers in surgery · 2022Article
- Image-guided minimally invasive endopancreatic surgery using a computer-assisted navigation system.Surgical endoscopy · 2021Article
- Pancreatic duct ligation reduces premalignant pancreatic lesions in a Kras model of pancreatic adenocarcinoma in mice.Scientific reports · 2020Article
- Possible involvement of HSP70 in pancreatic cancer cell proliferation after heat exposure and impact on RFA postoperative patient prognosis.Biochemistry and biophysics reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiofrequency energy has been used both experimentally and clinically to manage the pancreatic remnant after distal pancreatectomies. Our goal was to determine whether endoluminal radiofrequency (RF) ablation of the main pancreatic duct in large animals would be more efficient than glue occlusion as an exocrine pancreatic atrophy-inducing procedure. Thirty-four Landrace pigs were assigned to either the transpapilar (n = 16) or transection (n = 18) groups. The transection implied the pancreas neck was severed. In each of these groups the remaining distal pancreatic duct was occluded either by RF or by glue. In the transpapilar group complete atrophy was observed in all the RF cases, while atrophy was incomplete in all the members of the glue subgroup. The failure rate of the main pancreatic duct (usually expressed by a pseudocyst) in the transection groups was dramatically higher in the glue subgroup than the RF subgroups (9 out of 9 and 1 out of 9, respectively) and postoperative mortality occurred only in the glue subgroup (3 out of 9). These results show the superiority of endoluminal RF ablation over glue for main pancreatic duct occlusion, as seen by the degree of atrophy and fewer postoperative pancreatic fistulas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.