Evidence map›Paper›PMID 30975858›Full record

ArticleScience (New York, N.Y.)2019

Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides.

Pierre Buscaill, Balakumaran Chandrasekar, Nattapong Sanguankiattichai, Jiorgos Kourelis, Farnusch Kaschani, Emma L Thomas, Kyoko Morimoto, Markus Kaiser, Gail M Preston, Yuki Ichinose and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 156 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Specialization of independently acquired flagellar FliC proteins in plant-associatedProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Streamline Protocol forPlant direct · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Proteolysis in plant immunity.The Plant cell · 2024
    Review
  20. Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Pierre BuscaillDepartment of Plant Sciences, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-4756-1203
Balakumaran ChandrasekarDepartment of Plant Sciences, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-5696-6777
Nattapong SanguankiattichaiDepartment of Plant Sciences, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-4408-8262
Jiorgos KourelisDepartment of Plant Sciences, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-9007-1333
Farnusch KaschaniZMB Chemical Biology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany.
Emma L ThomasDepartment of Plant Sciences, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-7062-6568
Kyoko MorimotoDepartment of Plant Sciences, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-8113-9201
Markus KaiserZMB Chemical Biology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany.ORCID http://orcid.org/0000-0002-6540-8520
Gail M PrestonDepartment of Plant Sciences, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-3882-4438
Yuki IchinoseThe Graduate School of Environmental and Life Science, Okayama University, Japan.ORCID http://orcid.org/0000-0002-7767-7912
Renier A L van der HoornDepartment of Plant Sciences, University of Oxford, Oxford, UK. renier.vanderhoorn@plants.ox.ac.uk.
University of Oxford · GBUniversity of Duisburg-Essen · DEOkayama University of Science · JP

Funding

Biotechnology and Biological Sciences Research Council BB/M011224/1Biotechnology and Biological Sciences Research Council BB/R009236/1
6 · The paper itself

Abstract

Plants and animals recognize conserved flagellin fragments as a signature of bacterial invasion. These immunogenic elicitor peptides are embedded in the flagellin polymer and require hydrolytic release before they can activate cell surface receptors. Although much of flagellin signaling is understood, little is known about the release of immunogenic fragments. We discovered that plant-secreted β-galactosidase 1 (BGAL1) of

Indexed as

beta-GalactosidaseFlagellinGlycosylationHost-Pathogen InteractionsHydrolysisNicotianaPolymersPolysaccharidesPseudomonas syringaebeta-GalactosidaseFlagellinpolymerized flagellinPolymersPolysaccharides

Identifiers

PMID30975858
OpenAlexW2940431168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.