Evidence map›Paper›PMID 30975758›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Environmental DNA for improved detection and environmental surveillance of schistosomiasis.

Mita E Sengupta, Micaela Hellström, Henry C Kariuki, Annette Olsen, Philip F Thomsen, Helena Mejer, Eske Willerslev, Mariam T Mwanje, Henry Madsen, Thomas K Kristensen and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mita E SenguptaDepartment of Veterinary and Animal Sciences, University of Copenhagen, DK-1870 Frederiksberg, Denmark; msen@sund.ku.dk.ORCID 0000-0003-0748-3175
Micaela HellströmCentre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, DK-1350 Copenhagen K, Denmark.ORCID 0000-0002-4704-724X
Henry C KariukiDepartment of Microbiology and Parasitology, Kenya Methodist University, 60200 Meru, Kenya.
Annette OlsenDepartment of Veterinary and Animal Sciences, University of Copenhagen, DK-1870 Frederiksberg, Denmark.
Philip F ThomsenCentre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, DK-1350 Copenhagen K, Denmark.
Helena MejerDepartment of Veterinary and Animal Sciences, University of Copenhagen, DK-1870 Frederiksberg, Denmark.
Eske WillerslevCentre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, DK-1350 Copenhagen K, Denmark.
Mariam T MwanjeNeglected Tropical Diseases Unit, Division of Communicable Disease Prevention and Control, Ministry of Health, Nairobi, Kenya.
Henry MadsenDepartment of Veterinary and Animal Sciences, University of Copenhagen, DK-1870 Frederiksberg, Denmark.
Thomas K KristensenDepartment of Veterinary and Animal Sciences, University of Copenhagen, DK-1870 Frederiksberg, Denmark.
Anna-Sofie StensgaardCenter for Macroecology, Evolution and Climate, Natural History Museum of Denmark, University of Copenhagen, DK-2100 Copenhagen, Denmark.
Birgitte J VennervaldDepartment of Veterinary and Animal Sciences, University of Copenhagen, DK-1870 Frederiksberg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schistosomiasis is a water-based, infectious disease with high morbidity and significant economic burdens affecting >250 million people globally. Disease control has, with notable success, for decades focused on drug treatment of infected human populations, but a recent paradigm shift now entails moving from control to elimination. To achieve this ambitious goal, more sensitive diagnostic tools are needed to monitor progress toward transmission interruption in the environment, especially in low-intensity infection areas. We report on the development of an environmental DNA (eDNA)-based tool to efficiently detect DNA traces of the parasite

Indexed as

AnimalsDisease VectorsDNA, EnvironmentalEnvironmental MonitoringFecesHumansKenyaNeglected DiseasesSchistosoma mansoniSchistosomiasisSchistosomiasis mansoniSnailsDNA, Environmentaleliminationenvironmental DNASchistosoma mansonischistosomiasissnails

Identifiers

PMID30975758
PMCPMC6500138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.