Evidence map›Paper›PMID 30975699›Full record

ArticlePediatrics2019

Home Oxygen and 2-Year Outcomes of Preterm Infants With Bronchopulmonary Dysplasia.

Sara B DeMauro, Erik A Jensen, Carla M Bann, Edward F Bell, Anna Maria Hibbs, Susan R Hintz, Scott A Lorch

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 62 citations in OpenAlex.

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  11. Two-year outcomes following a randomised platelet transfusion trial in preterm infants.Archives of disease in childhood. Fetal and neonatal edition · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Sara B DeMauroDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; demauro@email.chop.edu.
Erik A JensenDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Carla M BannDivision of Statistical and Data Sciences, RTI International, Research Triangle Park, North Carolina.
Edward F BellDepartment of Pediatrics, The University of Iowa, Iowa City, Iowa.
Anna Maria HibbsDepartment of Pediatrics, Case Western Reserve University and Rainbow Babies and Children's Hospital, Cleveland, Ohio; and.
Susan R HintzDepartment of Pediatrics, Stanford University, Palo Alto, California.
Scott A LorchDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
University of Pennsylvania · USChildren's Hospital of Philadelphia · USRainbow Babies & Children's Hospital · USRTI International · USStanford University · USUniversity of Iowa · US

Funding

NICHD Neonatal Research Network -- Cincinnati Clinical CenterUG1HD027853 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI STEPHANIE L MERHAR · 2016 to 2026
$3.7M
NICHD Neonatal Research Network - Stanford UniversityUG1HD027880 · NICHD · STANFORD UNIVERSITY · PI Valerie Chock · 2016 to 2026
$3.3M
Multicenter Network of Neonatal Intensive Care Units-University of Texas at Houston (UT Houston) Clinical CenterUG1HD087229 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TYSON, JON E. · 2016 to 2022
$2.0M
Microbiome of the Airway and the Risk for Bronchopulmonary Dysplasia in the Lungs of Extreme Preterms: The MARBLE StudyK23HL136843 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI JENSEN, ERIK ALLEN · 2018 to 2022
$819k
NHLBI NIH HHS K23 HL136843NICHD NIH HHS UG1 HD027853NICHD NIH HHS UG1 HD027880NICHD NIH HHS UG1 HD087229
6 · The paper itself

Abstract

objectivesTo compare medical and developmental outcomes over the first 2 years of life in extremely preterm infants with bronchopulmonary dysplasia (BPD) who were discharged on supplemental oxygen via nasal cannula with outcomes of infants with a similar severity of respiratory illness who were discharged breathing in room air.

methodsWe performed a propensity score-matched cohort study. Eligible infants were born at <27 weeks' gestation, were receiving supplemental oxygen or respiratory support at 36 weeks' postmenstrual age, and were assessed at 18 to 26 months' corrected age. Study outcomes included growth, resource use, and neurodevelopment between discharge and follow-up. Outcomes were compared by using multivariable models adjusted for center and age at follow-up.

resultsA total of 1039 infants discharged on supplemental oxygen were propensity score matched 1:1 to infants discharged breathing in room air. Infants on oxygen had a marginal improvement in weight

conclusionsIn this matched cohort of infants with BPD, postdischarge oxygen was associated with marginally improved growth and increased resource use but no difference in neurodevelopmental outcomes. Ongoing and future trials are critical to assess the efficacy and safety of postdischarge supplemental oxygen for infants with BPD.

Indexed as

Bronchopulmonary DysplasiaChild, PreschoolCohort StudiesFemaleFollow-Up StudiesHome Care ServicesHumansInfantInfant, NewbornInfant, PrematureMaleOxygen Inhalation TherapyPatient DischargePropensity ScoreProspective StudiesRetrospective Studies

Identifiers

PMID30975699
PMCPMC6564066
OpenAlexW2940424372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.