ArticleMolecular cell2019
RRM Transcription Factors Interact with NLRs and Regulate Broad-Spectrum Blast Resistance in Rice.
Article in Molecular cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
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Who cites it
64 citing papers in PubMed, 180 citations in OpenAlex.
- An LRR-truncated NLR natural variant confers dual resistance to drought and blast in rice.Nature communications · 2026Article
- Alternative Polyadenylation Dynamics During the Rice Blast Immune Response.Molecular plant pathology · 2026Article
- Article
- The CCCH-tandem zinc-finger protein OsTZF1 positively regulates basal immunity but suppresses Piz-t-mediated blast resistance in rice.Plant communications · 2026Article
- Genetic identification of Pid3-1 and its regulatory role in promoting blast resistance in rice.G3 (Bethesda, Md.) · 2026Article
- An Auto-Activated NLR-Protein OsRGA3Plant biotechnology journal · 2026Article
- Soybean transcription factors GmHSF-01 and GmNF-YC03 regulate the GmSRC7BMC plant biology · 2026Article
- PyramidingPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Association and Transcriptome Analyses Identify OsCBP606 as a Calmodulin-Mediated Susceptibility Gene to Magnaporthe oryzae in Rice.Rice (New York, N.Y.) · 2026Article
- The LARGE1 controls grain size by repressing the interaction between PGL2 and APG in rice.The Plant journal : for cell and molecular biology · 2026Article
- Phenylalanine Ammonia-Lyase as a Key Enzyme in Tea Plant Resistance to Herbivory.International journal of molecular sciences · 2025Article
- The SNL Histone Deacetylase-Binding Factor GmHE13 Is a Novel Regulator of Soybean Hypocotyl Elongation.Plant biotechnology journal · 2025Article
- A Blast-Resistant NLR Gene Confers Drought Resistance by Competitively Interacting with an E3 Ligase to Protect Phenylalanine Ammonia-Lyase in Rice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Ferroptosis in plant immunity.Plant communications · 2025Review
- Precise genome editing of Dense and Erect Panicle 1 promotes rice sheath blight resistance and yield production in japonica rice.Plant biotechnology journal · 2025Article
- Enhancing the blast resistance of an elite thermo-sensitive genic male sterile line (TGMS) Longke638S and its derived hybrid varieties by incorporatingMolecular breeding : new strategies in plant improvement · 2025Article
- One stone for multiple birds: PigmR integrates multiple defense pathways for high and broad-spectrum blast resistance in rice.Stress biology · 2025Article
- A WRKY transcription factor confers broad-spectrum resistance to biotic stresses and yield stability in rice.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Status on Genetic Resistance to Rice Blast Disease in the Post-Genomic Era.Plants (Basel, Switzerland) · 2025Review
- Genetic engineering, including genome editing, for enhancing broad-spectrum disease resistance in crops.Plant communications · 2025Review
4 more citing papers are in PubMed but not listed here.
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Authors and funding
15 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nucleotide-binding site leucine-rich repeat (NLR) receptors perceive pathogen effectors and trigger plant immunity. However, the mechanisms underlying NLR-triggered defense responses remain obscure. The recently discovered Pigm locus in rice encodes a cluster of NLRs, including PigmR, which confers broad-spectrum resistance to blast fungus. Here, we identify PIBP1 (PigmR-INTERACTING and BLAST RESISTANCE PROTEIN 1), an RRM (RNA-recognition motif) protein that specifically interacts with PigmR and other similar NLRs to trigger blast resistance. PigmR-promoted nuclear accumulation of PIBP1 ensures full blast resistance. We find that PIBP1 and a homolog, Os06 g02240, bind DNA and function as unconventional transcription factors at the promoters of the defense genes OsWAK14 and OsPAL1, activating their expression. Knockout of PIBP1 and Os06 g02240 greatly attenuated blast resistance. Collectively, our study discovers previously unappreciated RRM transcription factors that directly interact with NLRs to activate plant defense, establishing a direct link between transcriptional activation of immune responses with NLR-mediated pathogen perception.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.