Evidence map›Paper›PMID 30975223›Full record

ArticleJournal of biomedical semantics2019

Moonstone: a novel natural language processing system for inferring social risk from clinical narratives.

Mike Conway, Salomeh Keyhani, Lee Christensen, Brett R South, Marzieh Vali, Louise C Walter, Danielle L Mowery, Samir Abdelrahman, Wendy W Chapman

Abstract read
In one paragraph

Article in Journal of biomedical semantics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  5. Using reasoning LLMs to extract SDOH events from clinical notes.Proceedings. IEEE International Conference on Healthcare Informatics · 2026
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  6. SDoH-GPT: using large language models to extract social determinants of health.Journal of the American Medical Informatics Association : JAMIA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mike ConwayDepartment of Biomedical Informatics, 421 Wakara Way, University of Utah, alt Lake City, 84108, UT, USA. mike.conway@utah.edu.ORCID 0000-0002-3209-8108
Salomeh KeyhaniSan Francisco VA Medical Center, 4150 Clement Street, San Francisco, 94121, CA, USA.
Lee ChristensenDepartment of Biomedical Informatics, 421 Wakara Way, University of Utah, alt Lake City, 84108, UT, USA.
Brett R SouthDepartment of Biomedical Informatics, 421 Wakara Way, University of Utah, alt Lake City, 84108, UT, USA.
Marzieh ValiSan Francisco VA Medical Center, 4150 Clement Street, San Francisco, 94121, CA, USA.
Louise C WalterSan Francisco VA Medical Center, 4150 Clement Street, San Francisco, 94121, CA, USA.
Danielle L MoweryDepartment of Biomedical Informatics, 421 Wakara Way, University of Utah, alt Lake City, 84108, UT, USA.
Samir AbdelrahmanDepartment of Biomedical Informatics, 421 Wakara Way, University of Utah, alt Lake City, 84108, UT, USA.
Wendy W ChapmanDepartment of Biomedical Informatics, 421 Wakara Way, University of Utah, alt Lake City, 84108, UT, USA.

Funding

An Evaluation of Novel Domains for Predicting 30-Day ReadmissionR01HL116522 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI KEYHANI, SALOMEH · 2013 to 2017
$3.3M
Information Extraction from EMRs to Predict Readmission following Acute Myocardial InfarctionR01HL130828 · NHLBI · DARTMOUTH COLLEGE · PI BROWN, JEREMIAH R, MATHENY, MICHAEL E. · 2016 to 2019
$3.1M
NHLBI NIH HHS R01 HL116522NHLBI NIH HHS R01 HL130828NHLBI NIH HHS R01HL130828
6 · The paper itself

Abstract

backgroundSocial risk factors are important dimensions of health and are linked to access to care, quality of life, health outcomes and life expectancy. However, in the Electronic Health Record, data related to many social risk factors are primarily recorded in free-text clinical notes, rather than as more readily computable structured data, and hence cannot currently be easily incorporated into automated assessments of health. In this paper, we present Moonstone, a new, highly configurable rule-based clinical natural language processing system designed to automatically extract information that requires inferencing from clinical notes. Our initial use case for the tool is focused on the automatic extraction of social risk factor information - in this case, housing situation, living alone, and social support - from clinical notes. Nursing notes, social work notes, emergency room physician notes, primary care notes, hospital admission notes, and discharge summaries, all derived from the Veterans Health Administration, were used for algorithm development and evaluation.

resultsAn evaluation of Moonstone demonstrated that the system is highly accurate in extracting and classifying the three variables of interest (housing situation, living alone, and social support). The system achieved positive predictive value (i.e. precision) scores ranging from 0.66 (homeless/marginally housed) to 0.98 (lives at home/not homeless), accuracy scores ranging from 0.63 (lives in facility) to 0.95 (lives alone), and sensitivity (i.e. recall) scores ranging from 0.75 (lives in facility) to 0.97 (lives alone).

conclusionsThe Moonstone system is - to the best of our knowledge - the first freely available, open source natural language processing system designed to extract social risk factors from clinical text with good (lives in facility) to excellent (lives alone) performance. Although developed with the social risk factor identification task in mind, Moonstone provides a powerful tool to address a range of clinical natural language processing tasks, especially those tasks that require nuanced linguistic processing in conjunction with inference capabilities.

Indexed as

Natural Language ProcessingSocial EnvironmentHealthHumansRisk FactorsNatural language processingSocial determinants of healthSoftware

Identifiers

PMID30975223
PMCPMC6458709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.