ArticleTrials2019
The effect of an expanded long-term periodization exercise training on physical fitness in patients with coronary artery disease: study protocol for a randomized controlled trial.
Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect Of An Expanded Long Term Periodization Exercise Training In Patients With Cardiovascular Disease: Central And Peripheral Adaptations
Chronic Adaptations in Cardiovagal Modulation and Cardiorespiratory Fitness in Patients With Coronary Artery Disease to a 12-week Heart Rate Variability-guided Training vs Traditional Aerobic Prescription Program: Study Protocol for a Randomized Controlled Trial
Who cites it
9 citing papers in PubMed.
- Impact of resistance training intensity on body composition and nutritional intake among college women with overweight and obesity: a cluster randomized controlled trial.Frontiers in public health · 2025Trial
- The effects of a comprehensive rehabilitation and intensive education program on anxiety, depression, quality of life, and major adverse cardiac and cerebrovascular events in unprotected left main coronary artery disease patients who underwent coronary artery bypass grafting.Irish journal of medical science · 2020Trial
- Periodizing Exercise Medicine Prescription for Patients with Cancer: A Narrative Opinion.Sports medicine (Auckland, N.Z.) · 2025Review
- The effect of cardiac rehabilitation prescription on medication complications and ET-1, WMSI in elderly patients with coronary heart disease.Journal of cardiothoracic surgery · 2024Article
- Review
- Effects of Two Different Exercise Training Programs Periodization on Anthropometric and Functional Parameters in People Living with HIV: A Randomized Clinical Trial.International journal of exercise science · 2022Article
- Periodization: Variation in the Definition and Discrepancies in Study Design.Sports medicine (Auckland, N.Z.) · 2021Review
- Intellectual disability, exercise and aging: the IDEA study: study protocol for a randomized controlled trial.BMC public health · 2020Article
- Quality of life after coronary artery bypass graft surgery - results of cardiac rehabilitation programme.Journal of exercise rehabilitation · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBenefits from cardiac rehabilitation (CR) programs are evidence-based and widely recognized. Less than 50% of people who participate in hospital-based CR programs maintain an exercise regime for as long as six months after completion. Little is known about interventions making the patients continue to exercise after the hospital-based formal program has ended. Methods to ensure sustained benefits of CR need to be tackled. Exercise periodization is a method typically used in sports training, but the impact of periodized exercise to yield optimal beneficial effects in cardiac patients is unclear. Therefore, the purpose of this trial is to evaluate the effects of a long-term exercise periodization on health-related physical fitness components such as cardiorespiratory endurance, muscular strength, skeletal muscle function, and body composition.
methodsFifty patients with coronary artery disease will be recruited among those who underwent the hospital-based CR phase. These patients will be randomized (1:1) into one of the following exercise groups: (1) periodized group; and (2) non-periodized group (exercise prescription based on standard guidelines). There will be four assessment time points: at baseline, and 3, 6, and 12 months after starting the exercise training program. At each time point, maximal and submaximal cardiorespiratory fitness, skeletal muscle deoxygenation dynamics, body composition by dual energy radiographic absorptiometry, functional fitness, maximal isometric and dynamic strength, physical activity, and quality of life will be assessed. This experimental design will last for 48 weeks with a frequency of three times per week for both groups. DISCUSSION: Most medium- to long-term exercise-based CR programs do not employ periodization or exercise progression. Randomized controlled trials are necessary to evaluate long-term periodization outcomes and assess the length of change observed in supervised CR programs. This study will contribute to generate evidence-based exercise prescription approaches to prolong the exercise training after the end of hospital-based CR programs.
trial registrationClinicalTrials.gov, NCT03335319 . Registered on 22 October 2017.
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