ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2019
The aorta after coarctation repair - effects of calibre and curvature on arterial haemodynamics.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Reverse Diagnostic Thinking for Aortic Coarctation Using the Renal Artery Bilateral Parvus et Tardus as a Clue: A Case Report.Clinical case reports · 2026Article
- Coarctation of the aorta and accelerated atherosclerosis: A contemporary review on the burden of atherosclerotic cardiovascular disease.International journal of cardiology. Congenital heart disease · 2025Article
- Aortic shape with high-acute isthmic angle post frozen elephant trunk reconstruction is associated with worse postoperative outcomes: Multisite, principal component analysis, retrospective study.JTCVS structural and endovascular · 2024Article
- Importance of Cardiovascular Magnetic Resonance Applied to Congenital Heart Diseases in Pediatric Age: A Narrative Review.Children (Basel, Switzerland) · 2024Review
- Article
- Aortic arch shape after arch repair predicts exercise capacity: a multicentre analysis.European heart journal open · 2024Article
- Three-dimensional aortic arch geometry and blood flow in neonates after surgical repair for aortic coarctation.Frontiers in cardiovascular medicine · 2024Article
- Aortic growth after arch reconstruction with patch augmentation: a 2-decade experience.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- Validation of a laser projection platform for the preparation of surgical patches used in paediatric cardiac surgery.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- Aortic shape variation after frozen elephant trunk procedure predicts aortic events: Principal component analysis study.JTCVS open · 2023Article
- Hypertension after coarctation repair-a systematic review.Translational pediatrics · 2022Review
- Four-Dimensional flow Magnetic Resonance Imaging for Assessment of Pediatric Coarctation of the Aorta.Journal of magnetic resonance imaging : JMRI · 2022Article
- Isolating the Effect of Arch Architecture on Aortic Hemodynamics Late After Coarctation Repair: A Computational Study.Frontiers in cardiovascular medicine · 2022Article
- Implementing Machine Learning in Interventional Cardiology: The Benefits Are Worth the Trouble.Frontiers in cardiovascular medicine · 2021Review
- Non-invasive assessment of ventriculo-arterial coupling using aortic wave intensity analysis combining central blood pressure and phase-contrast cardiovascular magnetic resonance.European heart journal. Cardiovascular Imaging · 2020Article
- Identified plasma proteins related to vascular structure are associated with coarctation of the aorta in children.Italian journal of pediatrics · 2020Article
- Correction to: The aorta after coarctation repair - effects of calibre and curvature on arterial haemodynamics.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
Abstract
backgroundAortic shape has been proposed as an important determinant of adverse haemodynamics following coarctation repair. However, previous studies have not demonstrated a consistent relationship between shape and vascular load. In this study, 3D aortic shape was evaluated using principal component analysis (PCA), allowing investigation of the relationship between 3D shape and haemodynamics.
methodsSixty subjects (38 male, 25.0 ± 7.8 years) with repaired coarctation were recruited. Central aortic haemodynamics including wave intensity analysis were measured noninvasively using a combination of blood pressure and phase contrast cardiovascular magnetic resonance (CMR). 3D curvature and radius data were derived from CMR angiograms. PCA was separately performed on 3D radius and curvature data to assess the role of arch geometry on haemodynamics. Clinical findings were corroborated using 1D vascular models.
resultsThere were no independent associations between 3D curvature and any hemodynamic parameters. However, the magnitude of the backwards compression wave was related to the 1st (r = - 0.36, p = 0.005), 3rd (r = 0.27, p = 0.036) and 4th (r = - 0.31, p = 0.017) principle components of radius. The 4th principle componentof radius also correlated with central aortic systolic pressure. These aortas had larger aortic roots, more transverse arch hypoplasia and narrower aortic isthmuses.
conclusionsThere are major modes of variation in 3D aortic shape after coarctation repair witha modest association between variation in aortic radius and pathological wave reflections, but not with 3D curvature. Taken together, these data suggest that shape is not the major determinant of vascular load following coarctation repair, and calibre is more important than curvature.
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