Evidence map›Paper›PMID 30975029›Full record

ArticleCancer biology & therapy2019

A regulatory circuit of circ-MTO1/miR-17/QKI-5 inhibits the proliferation of lung adenocarcinoma.

Binbin Zhang, Maolin Chen, Nan Jiang, Kefeng Shi, Runlin Qian

RetractedOpen access · bronzeAbstract readRetracted Publication
In one paragraph

Article in Cancer biology & therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Circular RNAs as biomarkers for lung cancer.Non-coding RNA research · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. The Roles of circMTO1 in Cancer.Frontiers in cell and developmental biology · 2021
    Review
  17. [Research Progress of Circular RNA in Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020
    Review
  18. Article
  19. Article
  20. Non-Coding RNAs in Lung Tumor Initiation and Progression.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Binbin Zhanga Thoracic surgery ward one , HeNan Provincial Chest Hospital , Zhengzhou , P.R. China.
Maolin Chena Thoracic surgery ward one , HeNan Provincial Chest Hospital , Zhengzhou , P.R. China.
Nan Jianga Thoracic surgery ward one , HeNan Provincial Chest Hospital , Zhengzhou , P.R. China.
Kefeng Shia Thoracic surgery ward one , HeNan Provincial Chest Hospital , Zhengzhou , P.R. China.
Runlin Qiana Thoracic surgery ward one , HeNan Provincial Chest Hospital , Zhengzhou , P.R. China.ORCID 0000-0003-2327-5472
Henan Provincial Chest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNA (circRNA) is a new class of non-coding RNA that plays a pivotal role in carcinogenesis. Recently, circ-MTO1 (hsa_circ_0007874) was shown to be a cancer-related circRNA. However, its role in lung adenocarcinoma (LUAD) has not been reported. Here, we found that circ-MTO1 was significantly down-regulated in LUAD, which was closely associated with malignant features and dismal prognosis. Enforced expression of circ-MTO1 suppressed the growth of LUAD cells both

Indexed as

Gene Expression Regulation, NeoplasticRNA, CircularRNA InterferenceAdenocarcinoma of LungAnimalsBiomarkers, TumorCell Line, TumorCell ProliferationDisease Models, AnimalHumansMiceMicroRNAsReceptors, NotchRNA-Binding ProteinsSignal TransductionBiomarkers, TumorMicroRNAsMIRN17 microRNA, humanMTO1 protein, humanReceptors, NotchRNA-binding protein QKI-5, humanRNA-Binding ProteinsRNA, Circularcirc-MTO1Circular RNAlung adenocarcinomamiRNAprognosisproliferation

Identifiers

PMID30975029
PMCPMC6606010
OpenAlexW2937778559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.