ArticleSensors (Basel, Switzerland)2019
A Gold Nanoclusters Film Supported on Polydopamine for Fluorescent Sensing of Free Bilirubin.
Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Ratiometric detection of bilirubin at nanomolar concentration based on β-cyclodextrin-capped gold nanoclusters with intrinsic dual-emission.Mikrochimica acta · 2025Article
- Interactions of coinage metal nanoclusters with low-molecular-weight biocompounds.Biophysical reviews · 2024Review
- Advances in Ultra-small Fluorescence Nanoprobes for Detection of Metal Ions, Drugs, Pesticides and Biomarkers.Journal of fluorescence · 2023Review
- Non-Enzymatically Colorimetric Bilirubin Sensing Based on the Catalytic Structure Disruption of Gold Nanocages.Sensors (Basel, Switzerland) · 2023Article
- Noninvasive direct bilirubin detection by spectral analysis of color images using a Mini-LED light source.Discover nano · 2023Article
- Langmuir and Langmuir-Blodgett Films of Gold and Silver Nanoparticles.Langmuir : the ACS journal of surfaces and colloids · 2023Review
- Biomarker sensing platforms based on fluorescent metal nanoclusters.Nanoscale advances · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Serum bilirubin is an important biomarker for the diagnosis of various types of liver diseases and blood disorders. A polydopamine/gold nanoclusters composite film was fabricated for the fluorescent sensing of free bilirubin. Bovine serum albumin (BSA)-stabilized gold nanoclusters (AuNCs) were used as probes for biorecognition. The polydopamine film was utilized as an adhesion layer for immobilization of AuNCs. When the composite film was exposed to free bilirubin, due to the complex that was formed between BSA and free bilirubin, the fluorescence intensity of the composite film was gradually weakened as the bilirubin concentration increased. The fluorescence quenching ratio (F₀/F) was linearly proportional to free bilirubin over the concentration range of 0.8~50 μmol/L with a limit of detection of 0.61 ± 0.12 μmol/L (S/N = 3). The response was quick, the film was recyclable, and common ingredients in human serum did not interfere with the detection of free bilirubin.
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Registered trials
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