Evidence map›Paper›PMID 30974796›Full record

ArticlePolymers2019

Photocrosslinkable Nanofibrous Asymmetric Membrane Designed for Wound Dressing.

Patrícia Alves, Marta Santos, Sabrina Mendes, Sónia P Miguel, Kevin D de Sá, Cátia S D Cabral, Ilídio J Correia, Paula Ferreira

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Photocurable Polymeric Blends for Surgical Application.Materials (Basel, Switzerland) · 2020
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Patrícia AlvesCIEPQPF, Department of Chemical Engineering, Universidade de Coimbra, P-3030 790 Coimbra, Portugal. palves@eq.uc.pt.
Marta SantosCIEPQPF, Department of Chemical Engineering, Universidade de Coimbra, P-3030 790 Coimbra, Portugal. martapatricia17@hotmail.com.
Sabrina MendesCIEPQPF, Department of Chemical Engineering, Universidade de Coimbra, P-3030 790 Coimbra, Portugal. sabmendes@gmail.com.
Sónia P MiguelCICS-UBI, Health Sciences Research Center, Universidade da Beira Interior, P-6200 506 Covilhã, Portugal. soniapmiguel@gmail.com.ORCID 0000-0001-7274-0399
Kevin D de SáCICS-UBI, Health Sciences Research Center, Universidade da Beira Interior, P-6200 506 Covilhã, Portugal. ringo.kesa@gmail.com.
Cátia S D CabralCICS-UBI, Health Sciences Research Center, Universidade da Beira Interior, P-6200 506 Covilhã, Portugal. catiadcabral@gmail.com.
Ilídio J CorreiaCIEPQPF, Department of Chemical Engineering, Universidade de Coimbra, P-3030 790 Coimbra, Portugal. icorreia@fcsaude.ubi.pt.
Paula FerreiraCIEPQPF, Department of Chemical Engineering, Universidade de Coimbra, P-3030 790 Coimbra, Portugal. pferreira@eq.uc.pt.
University of Beira Interior · PTUniversity of Coimbra · PT

Funding

Clinical Development of anti-OX40 and OX40LR01CA109563 · NCI · PROVIDENCE PORTLAND MEDICAL CENTER · PI CURTI, BRENDAN D · 2004 to 2008
$1.4M
Fundação para a Ciência e a Tecnologia SFRH/BD/109563/2015Fundação para a Ciência e a Tecnologia SFRH/BPD/69410/2010Operational Programme Competitiveness and Internationalization Project POCI-01-0145-FEDER-007491
6 · The paper itself

Abstract

Recently, the biomedical scientists who are working in the skin regeneration area have proposed asymmetric membranes as ideal wound dressings, since they are able to reproduce both layers of skin and improve the healing process as well as make it less painful. Herein, an electrospinning technique was used to produce new asymmetric membranes. The protective layer was composed of a blending solution between polycaprolactone and polylactic acid, whereas the underlying layer was comprised of methacrylated gelatin and chitosan. The chemical/physical properties, the in vitro hemo- and biocompatibility of the nanofibrous membranes were evaluated. The results obtained reveal that the produced membranes exhibited a wettability able to provide a moist environment at wound site. Moreover, the membranes' hemocompatibility and fibroblast cell adhesion, spreading and proliferation at the surface of the membranes were also noticed in the in vitro assays. Such results highlight the suitability of these asymmetric membranes for wound dressing applications.

Indexed as

asymmetric membranebiocompatibilityelectrospinningskin regeneration

Identifiers

PMID30974796
PMCPMC6523099
OpenAlexW2937133158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.