Evidence map›Paper›PMID 30974751›Full record

ArticleCells2019

Saturated Fatty Acid-Enriched Diet-Impaired Mitochondrial Bioenergetics in Liver From Undernourished Rats During Critical Periods of Development.

Aiany C Simões-Alves, Joao H Costa-Silva, Idelfonso B Barros-Junior, Reginaldo C da Silva Filho, Diogo A A Vasconcelos, Hubert Vidal, Béatrice Morio, Mariana P Fernandes

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Aiany C Simões-AlvesLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco-UFPE, Vitória de Santo Antão, PE 55608-680, Brazil. aiany_simoes@hotmail.com.
Joao H Costa-SilvaLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco-UFPE, Vitória de Santo Antão, PE 55608-680, Brazil. joao.hcsilva@ufpe.br.
Idelfonso B Barros-JuniorLaboratory of General Biochemistry, Molecular Biology and Exercise, Federal University of Pernambuco-UFPE, Vitória de Santo Antão, PE 55608-680, Brazil. idelfonso1992@hotmail.com.
Reginaldo C da Silva FilhoLaboratory of General Biochemistry, Molecular Biology and Exercise, Federal University of Pernambuco-UFPE, Vitória de Santo Antão, PE 55608-680, Brazil. regis.correia@hotmail.com.
Diogo A A VasconcelosLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Federal University of Pernambuco-UFPE, Vitória de Santo Antão, PE 55608-680, Brazil. diogovasconcelos13@yahoo.com.br.
Hubert VidalLaboratoire de Recherche en Cardiovasculaire, Métabolisme, Diabétologie et Nutrition (CarMeN), INSERM U1060, INRA U1397, Université Claude Bernard Lyon1, 69921 Oullins, France. hubertvidal@yahoo.com.
Béatrice MorioLaboratoire de Recherche en Cardiovasculaire, Métabolisme, Diabétologie et Nutrition (CarMeN), INSERM U1060, INRA U1397, Université Claude Bernard Lyon1, 69921 Oullins, France. beatrice.morio@inra.fr.ORCID 0000-0002-2418-1438
Mariana P FernandesLaboratory of General Biochemistry, Molecular Biology and Exercise, Federal University of Pernambuco-UFPE, Vitória de Santo Antão, PE 55608-680, Brazil. marianapfernandes@yahoo.com.br.
Universidade Federal de Pernambuco · BRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nutritional transition that the western population has undergone is increasingly associated with chronic metabolic diseases. In this work, we evaluated a diet rich in saturated fatty acids (hyperlipidic, HL) after weaning of the offspring rats submitted to maternal protein restriction on the hepatic mitochondrial bioenergetics. Wistar rats were mated and during gestation and lactation, mothers received control diets (NP, normal protein content 17%) or low protein (LP, 8% protein). After weaning, rats received either NL (normolipidic) or HL (+59% SFA) diets up to 90 days of life. It was verified that all respiratory states of hepatic mitochondria showed a reduction in the LP group submitted to the post-weaning HL diet. This group also presented greater mitochondrial swelling compared to controls, potentiated after Ca

Indexed as

Energy MetabolismAnimalsDiet, High-FatDiet, Protein-RestrictedFemaleLiverMaleMitochondriaOxidation-ReductionPregnancyPrenatal Exposure Delayed EffectsPrenatal Nutritional Physiological PhenomenaRatsRats, Wistarhyperlipidic dietoxidative metabolismprotein restriction

Identifiers

PMID30974751
PMCPMC6523252
OpenAlexW2936599277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.