ArticleThe Science of the total environment2019
Hospital effluent: A reservoir for carbapenemase-producing Enterobacterales?
Article in The Science of the total environment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An insight into the antibiotic resistance profiles of ESKAPE pathogens isolated from humans in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Antibiotic class-dependent degradation mechanisms and resistance gene elimination by dielectric barrier discharge cold plasma technology for wastewater treatment.RSC advances · 2026Review
- Metagenomic surveillance identifies a high-risk antibiotic resistance profile in community wastewater: a pilot study from Pakistan.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Carbapenemases: epidemiology, detection and management in a changing global landscape.JAC-antimicrobial resistance · 2026Review
- Molecular epidemiology of OXA-1054, a novel carbapenem-hydrolysing Class D β-lactamase, in Enterobacteriaceae isolated from wastewaters.npj antimicrobials and resistance · 2026Article
- Widespread Multidrug Resistance and Virulence Determinants inAntibiotics (Basel, Switzerland) · 2026Article
- Metagenomic profiling reveals distinct signatures of pathogens, antibiotic-resistance genes and human viruses in urban river mouths of the north-western Adriatic coast.Scientific reports · 2026Article
- Detection of Carbapenem-Resistant Bacteria in Skilled Nursing Facility Wastewater.The Journal of infectious diseases · 2026Article
- Persistence of viable opportunistic pathogens in a multi-stage natural wastewater treatment system.PloS one · 2026Article
- Article
- Skilled nursing facility wastewater surveillance: a SARS-CoV-2 and antimicrobial resistance detection pilot study.Journal of water and health · 2025Article
- Characterizing the co-existence of metallo-β-lactamase-producing and extended-spectrum β-lactamase-producingJournal of water and health · 2025Article
- Wastewater microbiology: occurrence and prevalence of antibiotic-resistant extended-spectrumJournal of water and health · 2025Article
- A Surveillance Study of Culturable and Antimicrobial-Resistant Bacteria in Two Urban WWTPs in Northern Spain.Antibiotics (Basel, Switzerland) · 2024Article
- Genomic epidemiology and longitudinal sampling of ward wastewater environments and patients reveals complexity of the transmission dynamics ofJAC-antimicrobial resistance · 2024Article
- Risk factors and molecular characterization of carbapenem resistant Escherichia coli recovered from a tertiary hospital in Fujian, China from 2021 to 2023.BMC microbiology · 2024Article
- Carbapenem-resistantJournal of water and health · 2024Article
- Deciphering the Role of WWTPs in Cold Environments as Hotspots for the Dissemination of Antibiotic Resistance Genes.Microbial ecology · 2023Article
- Detection and Characterization of Carbapenemase-ProducingAntibiotics (Basel, Switzerland) · 2023Article
- Molecular Characterization of Antibiotic Resistance Determinants inAntibiotics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial resistance is a major public health concern. Carbapenemase-producing Enterobacterales (CPE) represent a significant health threat as some strains are resistant to almost all available antibiotics. The aim of this research was to examine hospital effluent and municipal wastewater in an urban area in Ireland for CPE. Samples of hospital effluent (n = 5), municipal wastewater before (n = 5) and after (n = 4) the hospital effluent stream joined the municipal wastewater stream were collected over a nine-week period (May-June 2017). All samples were examined for CPE by direct plating onto Brilliance CRE agar. Isolates were selected for susceptibility testing to 15 antimicrobial agents in accordance with EUCAST criteria. Where relevant, isolates were tested for carbapenemase-encoding genes by real-time PCR. CPE were detected in five samples of hospital effluent, one sample of pre-hospital wastewater and three samples of post-hospital wastewater. Our findings suggest hospital effluent is a major contributor to CPE in municipal wastewater. Monitoring of hospital effluent for CPE could have important applications in detection and risk management of unrecognised dissemination of CPE in both the healthcare setting and the environment.
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Registered trials
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