Evidence map›Paper›PMID 30974326›Full record

ArticleNeuroImage. Clinical2019

Visual input drives increased occipital responsiveness and harmonized oscillations in multiple cortical areas in migraineurs.

Jan Mehnert, Daniel Bader, Guido Nolte, Arne May

Abstract read
In one paragraph

Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Application of EEG in migraine.Frontiers in human neuroscience · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cortical pain processing in migraine.Journal of neural transmission (Vienna, Austria : 1996) · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jan MehnertDepartment of Systems Neuroscience, University Medical Center Eppendorf, Hamburg, Germany.
Daniel BaderDepartment of Systems Neuroscience, University Medical Center Eppendorf, Hamburg, Germany.
Guido NolteDepartment of Neurophysiology and Pathophysiology, University Medical Center Eppendorf, Hamburg, Germany.
Arne MayDepartment of Systems Neuroscience, University Medical Center Eppendorf, Hamburg, Germany. Electronic address: a.may@uke.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraineurs are hypersensitive for most sensory domains like visual, auditory or somatosensory processing even outside of attacks. This behavioral peculiarity is mirrored by findings of cortical hyper-responsivity already in the interictal state. Using repetitive visual stimulation to elicit steady state visually evoked potentials (SSVEP) in 30 interictal episodic migraineurs and 30 controls we show hyper-responsivity of the visual cortex in the migraineurs. Additionally, the occipital regions were remarkably stronger coupled to the temporal, premotor and the anterior cingulate cortex than in headache free controls. These data suggest harmonized oscillations of different cortical areas as a response to visual input which might be driven by the cuneus. Furthermore, the increased coupling is modulated by the current state of the migraine cycle as the coupling was significantly stronger in patients with longer interictal periods.

Indexed as

Evoked Potentials, VisualAdultCortical SynchronizationElectroencephalographyFemaleHumansMigraine DisordersNeural PathwaysPhotic StimulationVisual CortexVisual PerceptionYoung AdultElectroencephalographyFunctional couplingNociceptionSource localizationTime-frequency analysisTrigeminal nervous system

Identifiers

PMID30974326
PMCPMC6458451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.