Evidence map›Paper›PMID 30974163›Full record

ArticleToxicology letters2019

Vasodilatory effect of formaldehyde via the NO/cGMP pathway and the regulation of expression of K

Yun Zhao, Jing Ge, Xiaoxiao Li, Qing Guo, Yuqing Zhu, Jing Song, Luoping Zhang, Shumao Ding, Xu Yang, Rui Li

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Functional Regulation of KFrontiers in pharmacology · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yun ZhaoHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China.
Jing GeHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China.
Xiaoxiao LiHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China.
Qing GuoHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China; School of Public Health, Huazhong University of Science and Technology, Hangkong Road, Wuhan, 430030, PR China.
Yuqing ZhuCentre of Stem Cell and Regenerative medicine, School of Medicine, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, PR China.
Jing SongHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China.
Luoping ZhangDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, 94720, USA.
Shumao DingHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China.
Xu YangHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China. Electronic address: yangxu@mail.ccnu.edu.cn.
Rui LiHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China. Electronic address: ruili@mail.ccnu.edu.cn.
Central China Normal University · CNUniversity of California, Berkeley · USZhejiang University · CN

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MCHALE, CLIONA · 1987 to 2025
$74.6M
Biomarkers of Formaldehyde Exposure and ToxicityR01ES017452 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ZHANG, LUOPING · 2009 to 2010
$743k
NIEHS NIH HHS P42 ES004705NIEHS NIH HHS R01 ES017452
6 · The paper itself

Abstract

Formaldehyde (FA), a well-known toxic gas molecule similar to nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H

Indexed as

AnimalsAorta, ThoracicCalcium Channels, L-TypeCyclic GMPFormaldehydeGene Expression RegulationKATP ChannelsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMaleNitric OxideRatsRats, WistarSignal TransductionVasodilationCalcium Channels, L-TypeCyclic GMPFormaldehydeKATP ChannelsKcnma1 protein, ratLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsNitric OxideFormaldehydeIon channelsNO/cGMP pathwayRat aortasVasorelaxation

Identifiers

PMID30974163
PMCPMC7790163
OpenAlexW2937107424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.