Evidence map›Paper›PMID 30974090›Full record

ArticleBrain research2019

Sex differences in insular functional connectivity in response to noxious visceral stimulation in rats.

Zhuo Wang, Yumei Guo, Emeran A Mayer, Daniel P Holschneider

Abstract read
In one paragraph

Article in Brain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Role of dorsal striatum circuits in relapse to opioid seeking after voluntary abstinence.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Orbitofrontal cortex and dorsal striatum functional connectivity predicts incubation of opioid craving after voluntary abstinence.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhuo WangDepartment of Psychiatry & Behavioral Sciences, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: zhuowang@usc.edu.
Yumei GuoDepartment of Psychiatry & Behavioral Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Emeran A MayerDepartments of Medicine, Physiology, Psychiatry and Biobehavioral Sciences, G Oppenheimer Center for Neurobiology of Stress and Resilience, University of California Los Angeles, Los Angeles, CA 90095, USA.
Daniel P HolschneiderDepartment of Psychiatry & Behavioral Sciences, University of Southern California, Los Angeles, CA 90089, USA; Departments of Neurology, Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA.

Funding

Women's Health and Functional Visceral Disorders CenterP50DK064539 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYER, EMERAN A · 2002 to 2017
$17.5M
PERCEPTION AND MODULATION OF VISCERAL SENSATIONSR01DK048351 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYER, EMERAN A · 1996 to 2019
$8.2M
NIDDK NIH HHS P50 DK064539NIDDK NIH HHS R01 DK048351
6 · The paper itself

Abstract

Insular cortex (INS) plays a critical role in pain processing and shows sex differences in functional activation during noxious visceral stimulation. Less is known regarding functional interactions within the INS and between this structure and other parts of the brain. Cerebral blood flow mapping was performed using [

Indexed as

Sex FactorsAnimalsBrainBrain MappingBrain StemCerebral CortexConnectomeFemaleMaleNeural PathwaysPainPrefrontal CortexRatsRats, WistarSex CharacteristicsColorectal distentionFunctional connectivityInsular cortexSex differencesVisceral pain

Identifiers

PMID30974090
PMCPMC6711370

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.