Evidence map›Paper›PMID 30973344›Full record

Trial reportJournal of medical Internet research2019

Effectiveness of Internet-Delivered Computerized Cognitive Behavioral Therapy for Patients With Insomnia Who Remain Symptomatic Following Pharmacotherapy: Randomized Controlled Exploratory Trial.

Daisuke Sato, Naoki Yoshinaga, Eiichi Nagai, Kazue Nagai, Eiji Shimizu

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  14. [Application and research progress of internet-based cognitive behavioral therapy for insomnia disorder].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Daisuke Sato *Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, Japan.ORCID 0000-0001-5562-8901
Naoki YoshinagaOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki, Japan.ORCID 0000-0002-4438-9746
Eiichi NagaiClinical Research Center, Chiba University Hospital, Chiba, Japan.ORCID 0000-0003-3862-3775
Kazue NagaiResearch and Education Center of Health Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan.ORCID 0000-0002-2562-2127
Eiji ShimizuDepartment of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, Japan.ORCID 0000-0002-6741-9338
Chiba Prefectural University of Health Sciences · JPChiba University · JPChiba University Hospital · JPGunma University · JPUniversity of Miyazaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn reality, pharmacotherapy still remains the most common treatment for insomnia.

objectiveThis study aimed to examine the effectiveness of our internet-delivered computerized cognitive behavioral therapy (ICBT) program as an adjunct to usual care (UC) compared with UC alone in patients with insomnia who remain symptomatic following hypnotics.

methodsWe recruited 23 patients with insomnia who remained symptomatic following pharmacologic treatment including benzodiazepines, and we conducted an exploratory randomized controlled trial. The primary outcome was the Pittsburgh Sleep Quality Index (PSQI) at week 6 of the treatment. Secondary outcomes were sleep onset latency, total sleep time, sleep efficiency, number of awakenings, refreshment and soundness of sleep, anxiety by Hospital Anxiety and Depression Scale, depression measured by the Center for Epidemiologic Studies Depression Scale, and quality of life (QOL) measured by the EuroQol-5D. All parameters were measured at weeks 0 (baseline), 6 (postintervention), and 12 (follow-up).

resultsThe adjusted mean reduction (-6.11) in PSQI at week 6 from baseline in the ICBT plus UC group was significantly (P<.001) larger than the adjusted mean reduction (0.40) in the UC alone group. Significant differences were also found in favor of ICBT plus UC for PSQI, sleep onset latency, sleep efficiency, number of awakenings, and depression at all assessment points. Refreshment, soundness of sleep, anxiety, and QOL improved by week 6 in ICBT plus UC compared with UC alone. There were no reports of adverse events in either group during the study.

conclusionsThese results indicated that our 6-week ICBT program is an effective treatment adjunct to UC for improving insomnia and related symptoms even after unsuccessful pharmacotherapy.

trial registrationUniversity Hospital Medical Information Network Clinical Trials Registry: UMIN000021509; https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023545 (Archived by WebCite at http://www.webcitation. org/75tCmwnYt).

Indexed as

Cognitive Behavioral TherapyFemaleHumansMaleMiddle AgedQuality of LifeSleep Initiation and Maintenance DisordersTreatment Outcomebenzodiazepinescognitive behavioral therapyinsomniainternetrandomized controlled trialresidual symptoms

Identifiers

PMID30973344
PMCPMC6482403
OpenAlexW2906367609

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.