Observational studyRenal failure2019
Gender-specific association between uric acid level and chronic kidney disease in the elderly health checkup population in China.
Observational study in Renal failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Article
- Serum Uric Acid Level as an Estimated Parameter That Predicts All-Cause Mortality in Patients with Hemodialysis.Journal of personalized medicine · 2025Article
- Correlation between obesity-related indices and hyperuricemia among the elderly population in China: A cross-sectional study.Medicine · 2025Article
- Gout and Hyperuricemia: A Narrative Review of Their Comorbidities and Clinical Implications.Journal of clinical medicine · 2024Review
- J-shaped Association between Serum Uric Acid Levels and the Prevalence of a Reduced Kidney Function: A Cross-sectional Study Using Japanese Health Examination Data.Internal medicine (Tokyo, Japan) · 2024Article
- Serum uric acid is associated with chronic kidney disease in elderly Chinese patients with diabetes.Renal failure · 2023Article
- Hyperuricaemia: prevalence and association with mortality in an elderly Finnish population.BMJ open · 2023Article
- Serum Uric Acid Levels and Their Association with Renal Function Decline and Kidney Disease Progression in Middle-Aged and Elderly Populations: A Retrospective Cohort Study.Journal of multidisciplinary healthcare · 2023Article
- Gender-Specific and U-Shaped Relationship Between Serum Uric Acid and All-Cause Mortality Among Chinese Older Adults: A National Population-Based Longitudinal Study.International journal of public health · 2023Article
- Sex Difference in the Associations among Hyperuricemia with New-Onset Chronic Kidney Disease in a Large Taiwanese Population Follow-Up Study.Nutrients · 2022Article
- The Association between Baseline, Changes in Uric Acid, and Renal Failure in the Elderly Chinese Individuals: A Prospective Study with a 3-Year Follow-Up.International journal of endocrinology · 2022Article
- The Potential of Prognostic Biomarkers of Uric Acid Levels in Coronary Heart Disease Among Aged Population: A Scoping Systematic Review of the Latest Cohort Evidence.Journal of multidisciplinary healthcare · 2022Article
- Hyperuricemia prevalence and its association with metabolic disorders: a multicenter retrospective real-world study in China.Annals of translational medicine · 2021Article
- Association between serum uric acid and new onset and progression of chronic kidney disease in a Japanese general population: Iki epidemiological study of atherosclerosis and chronic kidney disease.Clinical and experimental nephrology · 2021Observational
- Development and validation of a model for predicting acute kidney injury after cardiac surgery in patients of advanced age.Journal of cardiac surgery · 2021Article
- Risk Predictors of High Uric Acid Levels Among Patients with Type-2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- The Key Role of Uric Acid in Oxidative Stress, Inflammation, Fibrosis, Apoptosis, and Immunity in the Pathogenesis of Atrial Fibrillation.Frontiers in cardiovascular medicine · 2021Review
- Association between Serum Uric Acid Level and ESRD or Death in a Korean Population.Journal of Korean medical science · 2020Article
- Delayed treatment with an autophagy inhibitor 3-MA alleviates the progression of hyperuricemic nephropathy.Cell death & disease · 2020Article
- Uric Acid as a Potential Peripheral Biomarker for Disease Features in Huntington's Patients.Frontiers in neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the association between serum uric acid (SUA) levels with CKD in elderly health checkup population and explore the gender difference.
methodsA total of 4242 subjects were included in the cross-sectional study. All of the subjects participated in the annual checkup between June 2016 and June 2017. Chronic kidney disease (CKD) was defined by estimated glomerular filtration rate (eGFR) <60 ml/min per 1.73 m
resultThe prevalence of hyperuricemia was 22.2%, and it was significantly higher in male than in female (25.2% vs. 17%, p < .001). The prevalence of hyperuricemia increased with age, especially in the female. The prevalence of CKD was 27.8% in male and 20.2% in female (p < .001). Compared with the SUA first quartile, the multivariate-adjusted odds for CKD of fourth quartiles were 6.05 (95%CI: 4.32-8.49) in male and 8.21(95%CI: 5.37-12.54) in female.
conclusionOur finding showed gender-specific differences in the association between high SUA and an increased risk of CKD in the elderly population. The association of SUA and CKD was independent of other potential confounding factors including age, glucose, hypertension, HDL, TG and BMI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.