Evidence map›Paper›PMID 30973090›Full record

ArticleActa orthopaedica2019

Predicting individual knee range of motion, knee pain, and walking limitation outcomes following total knee arthroplasty.

Yong-Hao Pua, Cheryl Lian-Li Poon, Felicia Jie-Ting Seah, Julian Thumboo, Ross Allan Clark, Mann-Hong Tan, Hwei-Chi Chong, John Wei-Ming Tan, Eleanor Shu-Xian Chew, Seng-Jin Yeo

Registry-linked trialAbstract read
In one paragraph

Article in Acta orthopaedica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06086860 (Effects of Mulligan Mobilization With and Without Dry Needling in Runner's Knee), which is not on this map. Cited by 47 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06086860 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Mulligan Mobilization With and Without Dry Needling in Runner's Knee

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled40ConditionsRunner's KneeArmsMulligan mobilization with dry needling., Mulligan mobilization without dry needling
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yong-Hao Puaa Department of Physiotherapy , Singapore General Hospital , Singapore.
Cheryl Lian-Li Poona Department of Physiotherapy , Singapore General Hospital , Singapore.
Felicia Jie-Ting Seahb Department of Physiotherapy , Sengkang General Hospital , Singapore ;
Julian Thumbooc Department of Rheumatology and Immunology , Singapore General Hospital , Singapore.
Ross Allan Clarkd Research Health Institute , University of the Sunshine Coast , Sunshine Coast , Australia.
Mann-Hong Tane Department of Orthopaedic Surgery , Singapore General Hospital , Singapore.
Hwei-Chi Chonga Department of Physiotherapy , Singapore General Hospital , Singapore.
John Wei-Ming Tana Department of Physiotherapy , Singapore General Hospital , Singapore.
Eleanor Shu-Xian Chewa Department of Physiotherapy , Singapore General Hospital , Singapore.
Seng-Jin Yeoe Department of Orthopaedic Surgery , Singapore General Hospital , Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose - Up to 20% of patients are dissatisfied after total knee arthroplasty (TKA), mainly because of pain and restricted physical function. We developed a prediction model for 6-month knee range of motion, knee pain, and walking limitations in patients undergoing TKA surgery. Patients and methods - We performed a prospective cohort study of 4,026 patients who underwent elective, primary TKA between July 2013 and July 2017. Candidate predictors included demographic, clinical, psychosocial, and preoperative outcome measures. The outcomes of interest were (i) knee extension and flexion range of motion, (ii) knee pain rated on a 5-point ordinal scale, and (iii) self-reported maximum walk time at 6 months post TKA. For each outcome, we fitted a multivariable proportional odds regression model with bootstrap internal validation. Results - At 6 months post TKA, around 5% to 20% of patients had a flexion contracture ³ 10°, range of motion < 90°, moderate to severe knee pain, or a maximum walk time £ 15 minutes. The model c-indices (the probabilities to correctly discriminate between 2 patients with different levels of follow-up TKA outcomes) when evaluating these patients were 0.71, 0.79, 0.65, and 0.76, respectively. Each postoperative outcome was strongly influenced by the same outcome measure obtained preoperatively (all p-values < 0.001). Additional statistically significant predictors were age, sex, race, education level, diabetes mellitus, preoperative use of gait aids, contralateral knee pain, and psychological distress (all p-values < 0.001). Interpretation - We have developed models to predict, for individual patients, their likely post-TKA levels of knee extension and flexion range of motion, knee pain, and walking limitations. After external validation, they can potentially be used preoperatively to identify at-risk patients and to help patients set more realistic expectations about surgical outcomes.

Indexed as

ArthralgiaArthroplasty, Replacement, KneeMobility LimitationOsteoarthritis, KneePostoperative ComplicationsRange of Motion, ArticularAgedFemaleHumansKnee JointMaleMiddle AgedOutcome Assessment, Health CarePerioperative PeriodPrognosisRisk Assessment

Identifiers

PMID30973090
PMCPMC6461070

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.