Evidence map›Paper›PMID 30973066›Full record

ArticleTissue engineering. Part C, Methods2019

Optical Metric Assessed Engineered Tissues Over a Range of Viability States.

Leng-Chun Chen, Shiuhyang Kuo, William R Lloyd, Hyungjin Myra Kim, Cynthia L Marcelo, Stephen E Feinberg, Mary-Ann Mycek

Abstract read
In one paragraph

Article in Tissue engineering. Part C, Methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leng-Chun Chen1 Department of Biomedical Engineering, University of Michigan College of Engineering and Medical School, Ann Arbor, Michigan.
Shiuhyang Kuo2 Department of Oral and Maxillofacial Surgery, University of Michigan School of Dentistry, Ann Arbor, Michigan.
William R Lloyd1 Department of Biomedical Engineering, University of Michigan College of Engineering and Medical School, Ann Arbor, Michigan.
Hyungjin Myra Kim3 Center for Statistical Consultation and Research, University of Michigan School of Public Health, Ann Arbor, Michigan.
Cynthia L Marcelo4 Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
Stephen E Feinberg2 Department of Oral and Maxillofacial Surgery, University of Michigan School of Dentistry, Ann Arbor, Michigan.
Mary-Ann Mycek1 Department of Biomedical Engineering, University of Michigan College of Engineering and Medical School, Ann Arbor, Michigan.

Funding

Non-invasive Assessment of Tissue Engineered Human Oral MucosaR01DE019431 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FEINBERG, STEPHEN ELLIOTT, MYCEK, MARY-ANN · 2009 to 2012
$3.0M
NIDCR NIH HHS R01 DE019431
6 · The paper itself

Abstract

Many conventional methods to assess engineered tissue morphology and viability are destructive techniques with limited utility for tissue constructs intended for implantation in patients. Sterile label-free optical molecular imaging methods analyzed tissue endogenous fluorophores without staining, noninvasively and quantitatively assessing engineered tissue, in lieu of destructive assessment methods. The objective of this study is to further investigate label-free optical metrics and their correlation with destructive methods. Tissue-engineered constructs (

Indexed as

Optical ImagingTissue SurvivalCell SurvivalHumansKeratinocytesMolecular ImagingStaining and LabelingTissue EngineeringTissue Scaffoldsimaginglabel-freenoninvasiveoptical metrictissue engineeringviability

Identifiers

PMID30973066
PMCPMC6535959

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.