Evidence map›Paper›PMID 30973021›Full record

SynthesisHealth communication2020

Direct-to-Consumer Advertising of Prescription Drugs and the Patient-Prescriber Encounter: A Systematic Review.

Jessica T DeFrank, Nancy D Berkman, Leila Kahwati, Katherine Cullen, Kathryn J Aikin, Helen W Sullivan

Abstract readSystematic Review
In one paragraph

Synthesis in Health communication, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pharmaceutical policies: effects of policies regulating drug marketing.The Cochrane database of systematic reviews · 2023
    Pooled it
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  14. Knowledge and Practice of Antibiotic Management and Prudent Prescribing among Polish Medical Doctors.International journal of environmental research and public health · 2022
    Article
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  16. Article
  17. EDITORIAL COMMENT.Urology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jessica T DeFrankRTI International, Social Policy, Health & Economics Research.
Nancy D BerkmanRTI International, Social Policy, Health & Economics Research.
Leila KahwatiRTI International, Social Policy, Health & Economics Research.
Katherine CullenRTI International, Social Policy, Health & Economics Research.
Kathryn J AikinOffice of Prescription Drug Promotion, US Food and Drug Administration.
Helen W SullivanOffice of Prescription Drug Promotion, US Food and Drug Administration.

Funding

FDA HHS HHSF223201510002BIntramural FDA HHS FD999999
6 · The paper itself

Abstract

We systematically reviewed the research on patients' and prescribers' perceptions of, and self-reported behaviors prompted by, exposure to direct-to-consumer advertising (DTCA) (For ease of reading we use the term "advertising" to encompass advertising and promotional labeling. Broad use of this term does not imply endorsement by FDA) of prescription drugs that occurs in the context of a clinical encounter. This research offers an important perspective on the broader goal of incorporating patient and prescriber voices in decision-making. Outcomes included patient information seeking, medication adherence, patient requests for DTCA-promoted prescription drugs, prescribing behaviors, and perceptions of the patient-prescriber relationship and interactions. We searched PubMed and other databases from 1982-2017 and identified 38 studies meeting our study criteria. Of these, 24 studies used patient-reported outcomes and 18 used prescriber-reported outcomes (four used both). Studies suggested some potential benefits of exposure to DTCA, including patients' enhanced information-seeking, increased patient requests for appropriate prescriptions (when addressing potential underuse) and patients' perceptions of higher-quality interactions with prescribers. Most prescribers perceived a neutral influence on the quality of their clinical interactions with patients regarding DTCA. Harms included patients receiving prescriptions for drugs that were not appropriate for them or that the patients did not need, and the potential for DTCA to interfere with medication adherence in some populations, such as those with mental illness. The potential benefits of DTCA on the patient-provider encounter must be balanced with the potential for harms.

Indexed as

Direct-to-Consumer AdvertisingPrescription DrugsAdvertisingHumansMedication AdherencePrescription Drugs

Identifiers

PMID30973021
PMCPMC8218606

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.