Evidence map›Paper›PMID 30972642›Full record

ArticleJournal of ultrasound2019

The comparison of accuracy of ultrasonographic features versus ultrasound-guided fine-needle aspiration cytology in diagnosis of malignant thyroid nodules.

Mehrdad Nabahati, Zoleika Moazezi, Soude Fartookzadeh, Rahele Mehraeen, Naser Ghaemian, Majid Sharbatdaran

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of ultrasound, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mehrdad NabahatiDepartment of Radiology, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran.
Zoleika MoazeziDepartment of Endocrinology, Rohani Hospital, Babol University of Medical Sciences, Ganjafrooz Street, Babol, Mazandaran, 47176-47745, Iran. zmoazezi@yahoo.com.ORCID http://orcid.org/0000-0001-5915-9460
Soude FartookzadehStudent Research Committee, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
Rahele MehraeenDepartment of Radiology, Rohani Hospital, Babol University of Medical Sciences, Babol, Iran.
Naser GhaemianDepartment of Radiology, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran.
Majid SharbatdaranDepartment of Pathology, Rohani Hospital, Babol University of Medical Sciences, Babol, Iran.
Babol University of Medical Sciences · IR

Funding

Vice Chancellor for the Research of Babol University of Medical Sciences 9603612
6 · The paper itself

Abstract

purposeTo compare the diagnostic accuracy of sonographic features with ultrasound-guided fine-needle aspiration (FNA) cytology in the detection of malignant thyroid nodules.

methodsThis analytical cross-sectional study was conducted on patients with the diagnosis of thyroid nodule, who underwent ultrasound-guided FNA in Shahid Beheshti teaching hospital, Babol, northern Iran, between 2015 and 2017. The characteristics of the nodules obtained from ultrasonography were recorded. Regression analysis was used to assess the relation between sonographic findings and malignancy. We also used a receiver operator characteristics analysis to estimate the ability of ultrasound to predict the characteristic features of malignancy, as estimated by the area under the curve.

resultsIn total, 898 thyroid nodules were included in the study, of which 55 (6.1%) were malignant and 843 (93.9%) were benign. There were significant positive associations between malignancy and hypoechogenicity [odds ratio (OR) 3.577, 95% confidence interval (CI) 2.045-6.256], fine calcification (OR 5.849, 95% CI 2.642-12.949), irregular margin (OR 4.366, 95% CI 2.284-8.345) and taller-than-wide shape (OR 5.199, 95% CI 2.125-12.721). The overall accuracies of hypoechogenicity, irregular margin, taller-than-wide shape and fine calcification were 0.804, 0.729, 0.705 and 0.575, respectively.

conclusionAccording to the present study, the use of ultrasonography (along with ultrasound-guided FNA) is very effective in the diagnosis, follow-up, and indication for surgery of a thyroid nodule.

Indexed as

AdolescentAdultAgedAged, 80 and overBiopsy, Fine-NeedleCross-Sectional StudiesFemaleHumansImage-Guided BiopsyMaleMiddle AgedReproducibility of ResultsThyroid NoduleUltrasonographyYoung AdultBiopsyCytologyFine-needle aspirationUltrasonography

Identifiers

PMID30972642
PMCPMC6704223
OpenAlexW2939859331

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.