Evidence map›Paper›PMID 30972551›Full record

ArticleVirchows Archiv : an international journal of pathology2019

Challenging the prognostic impact of the new WHO and TNM classifications with special emphasis on HPV status in penile carcinoma.

Sebastian Hölters, Oybek Khalmurzaev, Alexey Pryalukhin, Philine Loertzer, Martin Janssen, Julia Heinzelbecker, Stefan Ueberdiek, Thorsten Pfuhl, Sigrun Smola, Abbas Agaimy and 10 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Assessment of EGFR and HER2 expression in penile cancer as potential therapeutic targets.Virchows Archiv : an international journal of pathology · 2026
    Article
  3. Prognostic value of the tumor immune microenvironment, PD-L1 and p16Virchows Archiv : an international journal of pathology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 2 countries.

Sebastian HöltersDepartment of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Oybek KhalmurzaevDepartment of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Alexey PryalukhinInstitute of Pathology, Saarland University Medical Centre, Homburg, Germany.
Philine LoertzerDepartment of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Martin JanssenDepartment of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Julia HeinzelbeckerDepartment of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Stefan UeberdiekDepartment of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Thorsten PfuhlInstitute of Virology, Saarland University, Homburg, Germany.
Sigrun SmolaInstitute of Virology, Saarland University, Homburg, Germany.
Abbas AgaimyInstitute of Pathology, University Erlangen-Nuremberg, Erlangen, Germany.
Carol GeppertInstitute of Pathology, University Erlangen-Nuremberg, Erlangen, Germany.
Hagen LoertzerClinic of Urology and Paediatric Urology, Westpfalz-Klinikum, Kaiserslautern, Germany.
Xaver KrahClinic of Urology, Helios Kliniken, Blankenhain, Germany.
Heiko WunderlichClinic of Urology and Paediatric Urology, St. Georg Klinikum, Eisenach, Germany.
Stefan WagenpfeilInstitute for Medical Biometry, Epidemiology and Medical Informatics, Saarland University, Homburg, Germany.
Rainer M BohleInstitute of Pathology, Saarland University Medical Centre, Homburg, Germany.
Michael StöckleDepartment of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany.
Vsevolod MatveevDepartment of Urology, Federal State Budgetary Institution "N.N. Blokhin National Medical Research Center of Oncology" оf the Ministry of Health of the Russian Federation, Moscow, Russian Federation.
Arndt HartmannInstitute of Pathology, University Erlangen-Nuremberg, Erlangen, Germany.
Kerstin JunkerDepartment of Urology and Paediatric Urology, Saarland University, Kirrberger Straße 100, 66424, Homburg, Germany. kerstin.junker@uks.eu.ORCID http://orcid.org/0000-0002-0873-8128
Saarland University · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEMinistry of Health of the Russian Federation · RUHelios Kliniken · DEKlinikum St. Georg · DEUniversitätsmedizin Göttingen · DEWestpfalz Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evidence concerning prognostic parameters for clinical decision-making in penile cancer is either weak or missing. We therefore analysed the prognostic value of the revised TNM and WHO classification systems on relapse and survival with special emphasis on HPV status. We collected clinical data and tissue samples of 121 patients from centres in Germany and Russia. HPV genotyping and p16

Indexed as

AdultAgedAged, 80 and overCarcinoma, Squamous CellHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm StagingPapillomaviridaePapillomavirus InfectionsPenile NeoplasmsPrognosisWorld Health OrganizationHPVPrognosisSquamous penile carcinoma

Identifiers

PMID30972551
OpenAlexW2936585880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.