Evidence map›Paper›PMID 30972464›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2020

In vivo kinematics and ligamentous function of the knee during weight-bearing flexion: an investigation on mid-range flexion of the knee.

Zhitao Rao, Chaochao Zhou, Willem A Kernkamp, Timothy E Foster, Hany S Bedair, Guoan Li

Open access · greenAbstract read
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Zhitao RaoOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital/Harvard Medical School, 159 Wells Ave, Newton, MA, 02459, USA.
Chaochao ZhouOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital/Harvard Medical School, 159 Wells Ave, Newton, MA, 02459, USA.
Willem A KernkampOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital/Harvard Medical School, 159 Wells Ave, Newton, MA, 02459, USA.
Timothy E FosterOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital/Harvard Medical School, 159 Wells Ave, Newton, MA, 02459, USA.
Hany S BedairOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital/Harvard Medical School, 159 Wells Ave, Newton, MA, 02459, USA.
Guoan LiOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital/Harvard Medical School, 159 Wells Ave, Newton, MA, 02459, USA. gli1@partners.org.
Massachusetts General Hospital · USNewton Wellesley Hospital · USHarvard University · USTongji University · CN

Funding

In vivo ACL Reconstruction BiomechanicsR01AR055612 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LI, GUOAN · 2008 to 2012
$1.9M
In-Vivo Ligamentous Tension of the KneeR21AR051078 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LI, GUOAN · 2006 to 2007
$418k
Foundation for the National Institutes of Health R-01 AR055612NIAMS NIH HHS R01 AR055612NIAMS NIH HHS R21 AR051078
6 · The paper itself

Abstract

purposeTo investigate the in vivo femoral condyle motion and synergistic function of the ACL/PCL along the weight-bearing knee flexion.

methodsTwenty-two healthy human knees were imaged using a combined MRI and dual fluoroscopic imaging technique during a single-legged lunge (0°-120°). The medial and lateral femoral condyle translation and rotation (measured using geometric center axis-GCA), and the length changes of the ACL/PCL were analyzed at: low (0°-30°), mid-range (30°-90°) and high (90°-120°) flexion of the knee.

resultsAt low flexion (0°-30°), the strains of the ACL and the posterior-medial bundle of the PCL decreased. The medial condyle showed anterior translation and lateral condyle posterior translation, accompanied with a sharp increase in external GCA rotation (internal tibial rotation). As the knee continued flexion in mid-range (30°-90°), both ACL and PCL were slack (with negative strain values). The medial condyle moved anteriorly before 60° of flexion and then posteriorly, accompanied with a slow increase of GCA rotation. As the knee flexed in high flexion (90°-120°), only the PCL had increasingly strains. Both medial and lateral condyles moved posteriorly with a rather constant GCA rotation.

conclusionsThe ACL and PCL were shown to play a reciprocal and synergistic role during knee flexion. Mid-range reciprocal anterior-posterior femoral translation or laxity corresponds to minimal constraints of the ACL and PCL, and may represent a natural motion character of normal knees. The data could be used as a valuable reference when managing the mid-range "instability" and enhancing high flexion capability of the knee after TKAs. LEVEL OF EVIDENCE: Level IV.

Indexed as

AdultAnterior Cruciate LigamentBiomechanical PhenomenaFemaleFemurFluoroscopyHumansKnee JointMagnetic Resonance ImagingMaleMiddle AgedPosterior Cruciate LigamentRange of Motion, ArticularRotationTibiaWeight-BearingACLHigh flexionIn vivo knee kinematicsMid-range instabilityPCLTKA

Identifiers

PMID30972464
PMCPMC6786938
OpenAlexW2935988083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.