Evidence map›Paper›PMID 30972229›Full record

ArticleAJP reports2019

Effect of a High-Fat Diet and Metformin on Placental mTOR Signaling in Mice.

Matthew R Grace, Sarah K Dotters-Katz, Chunxiao Zhou, Tracy Manuck, Kim Boggess, Victoria Bae-Jump

Open access · goldAbstract read
In one paragraph

Article in AJP reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Interaction between Metformin, Folate and Vitamin BInternational journal of molecular sciences · 2021
    Review
  8. Article
  9. Review
  10. Developmental effects ofTrends in developmental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Matthew R GraceTennessee Maternal Fetal Medicine and the University of Tennessee, Division of Obstetrics and Gynecology, Department of Clinical Medicine Education, Nashville, Tennessee.
Sarah K Dotters-KatzDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina.
Chunxiao ZhouDivision of Gynecologic Oncology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Tracy ManuckDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Kim BoggessDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Victoria Bae-JumpDivision of Gynecologic Oncology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
University of North Carolina at Chapel Hill · USDuke University · USTennessee Department of Education · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
NIDDK NIH HHS P30 DK056350NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

high-fat dietmetforminmicemTOR

Identifiers

PMID30972229
PMCPMC6456331
OpenAlexW2936384992

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.