Evidence map›Paper›PMID 30972070›Full record

ArticleFrontiers in immunology2019

Halted Lymphocyte Egress via Efferent Lymph Contributes to Lymph Node Hypertrophy During Hypercholesterolemia.

Meng Hwee Daniel Tay, Swee Yeng Jason Lim, Yew Fai Ivan Leong, Chung Hwee Thiam, Kar Wai Tan, Federico Tesio Torta, Pradeep Narayanaswamy, Markus Wenk, Véronique Angeli

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  10. Lymphatic endothelial cells of the lymph node.Nature reviews. Immunology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Meng Hwee Daniel TayImmunology Programme, Department of Microbiology and Immunology, Life Science Institute, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Swee Yeng Jason LimImmunology Programme, Department of Microbiology and Immunology, Life Science Institute, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yew Fai Ivan LeongImmunology Programme, Department of Microbiology and Immunology, Life Science Institute, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Chung Hwee ThiamImmunology Programme, Department of Microbiology and Immunology, Life Science Institute, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Kar Wai TanImmunology Programme, Department of Microbiology and Immunology, Life Science Institute, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Federico Tesio TortaDepartment of Biochemistry, Life Science Institute, SLING-Singapore Lipidomics Incubator, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Pradeep NarayanaswamyDepartment of Biochemistry, Life Science Institute, SLING-Singapore Lipidomics Incubator, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Markus WenkDepartment of Biochemistry, Life Science Institute, SLING-Singapore Lipidomics Incubator, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Véronique AngeliDepartment of Biochemistry, Life Science Institute, SLING-Singapore Lipidomics Incubator, Yoon Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyslipidemia is a central component of atherosclerosis and metabolic syndrome linked to chronic inflammation and immune dysfunction. Previously, we showed that hypercholesterolemic apolipoprotein E knock out (apoE

Indexed as

AnimalsApolipoproteins ECell MovementChemokine CCL21HypercholesterolemiaHypertrophyLymphatic VesselsLymph NodesLymphocytesLysophospholipidsMaleMiceMice, Inbred C57BLMice, Knockout, ApoESphingosineApoe protein, mouseApolipoproteins EChemokine CCL21LysophospholipidsSphingosinesphingosine 1-phosphatedyslipidemialymphatic vessellymph nodelymphocyte egressmouse model

Identifiers

PMID30972070
PMCPMC6446103
OpenAlexW2919367802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.