ArticleFrontiers in microbiology2019
Relating Urban Biodiversity to Human Health With the 'Holobiont' Concept.
Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Randomized controlled trial on the efficacy of forest walking compared to urban walking in enhancing mucosal immunity.Scientific reports · 2025Trial
- Urbanization-Associated Microbial Diversity Loss and Its Impact on Elderly Health: Integrating Environmental and Host Microbiome Dynamics.Environmental microbiology · 2026Article
- Cultivated Vegetation Shapes Diversity and Stability of Spontaneous Herbaceous Communities in Residential Green Spaces.Ecology and evolution · 2026Article
- Environmental microbiota transfer from forest soil into urban homes: a proof-of-principle study.Microbiome · 2026Article
- Sustainable rewilding of urban spaces increases microbial diversity.Sustainable microbiology · 2026Article
- Impacts of Breaching Planetary Boundaries on Human Health: Current and Future Threats.GeoHealth · 2025Review
- Rethinking Conservation in the Anthropocene-The Case of Holobionts.Disease biology, genetics, and socioecology · 2025Article
- Heterogeneity of the rearing environment enhances diversity of microbial communities in intensive farming.Animal microbiome · 2024Article
- The potential importance of the built-environment microbiome and its impact on human health.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Reduce, reinforce, and replenish: safeguarding the early-life microbiota to reduce intergenerational health disparities.Frontiers in public health · 2024Review
- A Novel Handrub Tablet Loaded with Pre- and Post-Biotic Solid Lipid Nanoparticles Combining Virucidal Activity and Maintenance of the Skin Barrier and Microbiome.Pharmaceutics · 2023Article
- The Concept of One Health for Allergic Diseases and Asthma.Allergy, asthma & immunology research · 2023Review
- Captivity and Animal Microbiomes: Potential Roles of Microbiota for Influencing Animal Conservation.Microbial ecology · 2023Review
- Temporary establishment of bacteria from indoor plant leaves and soil on human skin.Environmental microbiome · 2022Article
- Perspectives on Inequity and Health Disparities in Chile and Their Relationship to Microbial Ecology.mSystems · 2022Article
- Review
- Pathogen Control in the Built Environment: A Probiotic-Based System as a Remedy for the Spread of Antibiotic Resistance.Microorganisms · 2022Article
- Examining the paradox of urban disease ecology by linking the perspectives of Urban One Health and Ecology with Cities.Urban ecosystems · 2022Article
- Rare genera differentiate urban green space soil bacterial communities in three cities across the world.Access microbiology · 2022Article
- Metabarcoding of Soil Fungi from Different Urban Greenspaces Around Bournemouth in the UK.EcoHealth · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A relatively unaccounted ecosystem service from biodiversity is the benefit to human health via symbiotic microbiota from our environment. This benefit occurs because humans evolved alongside microbes and have been constantly exposed to diverse microbiota. Plants and animals, including humans, are organised as a host with symbiotic microbiota, whose collective genome and life history form a single holobiont. As such, there are interdependencies between biodiversity, holobionts, and public health which lead us to argue that human health outcomes could be improved by increasing contact with biodiversity in an urban context. We propose that humans, like all holobionts, likely require a diverse microbial habitat to appropriate resources for living healthy, long lives. We discuss how industrial urbanisation likely disrupts the symbiosis between microbiota and their hosts, leading to negative health outcomes. The industrialised urban habitat is low in macro and microbial biodiversity and discourages contact with beneficial environmental microbiota. These habitat factors, alongside diet, antibiotics, and others, are associated with the epidemic of non-communicable diseases in these societies. We suggest that restoration of urban microbial biodiversity and micro-ecological processes through microbiome rewilding can benefit holobiont health and aid in treating the urban non-communicable disease epidemic. Further, we identify research gaps and some solutions to economic and strategic hurdles in applying microbiome rewilding into daily urban life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.