Evidence map›Paper›PMID 30971962›Full record

ArticleFrontiers in psychiatry2019

Sex-Gender Comparisons in Comorbidities of Children and Adolescents With High-Functioning Autism Spectrum Disorder.

Lucia Margari, Roberto Palumbi, Antonia Peschechera, Francesco Craig, Concetta de Giambattista, Patrizia Ventura, Francesco Margari

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. [Adolescent depressive disorder: prevalence, risk factors, current status of diagnosis and treatment, and challenges].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Article
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  9. Article
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  12. Observational
  13. Article
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  16. Problematic eating behaviours of autistic women-A scoping review.European eating disorders review : the journal of the Eating Disorders Association · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucia MargariBasic Medical Sciences Neuroscience and Sense Organs Department, University of Bari Aldo Moro, Bari, Italy.
Roberto PalumbiBasic Medical Sciences Neuroscience and Sense Organs Department, University of Bari Aldo Moro, Bari, Italy.
Antonia PeschecheraBasic Medical Sciences Neuroscience and Sense Organs Department, University of Bari Aldo Moro, Bari, Italy.
Francesco CraigUnit for Severe Disabilities in Developmental Age and Young Adults, Developmental Neurology and Neurorehabilitation, Scientific Institute IRCCS E. Medea, Brindisi, Italy.
Concetta de GiambattistaBasic Medical Sciences Neuroscience and Sense Organs Department, University of Bari Aldo Moro, Bari, Italy.
Patrizia VenturaBasic Medical Sciences Neuroscience and Sense Organs Department, University of Bari Aldo Moro, Bari, Italy.
Francesco MargariBasic Medical Sciences Neuroscience and Sense Organs Department, University of Bari Aldo Moro, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last few years, new studies focused their attention on the gender-related features in high-functioning autism spectrum disorder (HFA), often leading to controversial results. Another interesting aspect of these subtype of patients is linked to the complexity of clinical presentation, where besides core symptoms, other co-occurrence disorders may complicate the diagnostic evaluation. Therefore, we retrospectively studied 159 HFA patients, male and female, investigating their comorbidities and to find any gender difference. For each patient, were evaluated the presence/absence, type and gender distribution of psychopathological comorbidities, according to DSM-5 diagnostic criteria. The total sample was divided in 100 male and 59 female patients, age and intelligence quotient matched. In our sample, the psychiatric comorbidities observed were Attention Deficit Hyperactivity Disorder, Anxiety Disorders, Depressive Disorders, Bipolar Disorder, Obsessive-Compulsive Disorder, and Anorexia Nervosa. No statistical significant differences were found between male and female HFA patients comorbidities except for Anorexia Nervosa. In both male and female patients, attention deficit and hyperactivity disorder and anxiety disorders were found in high percentage. In conclusion, our investigation showed that a statistical significant difference of comorbidity between male and female HFA patients was found only for AN diagnosis. However, the question about the distinction between female and male HFA patients remains quite interesting and an open area of research for future studies.

Indexed as

ADHDanorexia nervosaanxiety disordersautism spectrum disordergender distributionhigh-functioningmood disorderspsychopathological comorbidities

Identifiers

PMID30971962
PMCPMC6445051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.