Evidence map›Paper›PMID 30971959›Full record

ArticleFrontiers in psychiatry2019

Acute Effects of Aerobic Exercise on Executive Function and Attention in Adult Patients With ADHD.

Aylin Mehren, Jale Özyurt, Alexandra P Lam, Mirko Brandes, Helge H O Müller, Christiane M Thiel, Alexandra Philipsen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 10 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 10 syntheses or guidelines pooled it, 94 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Aylin MehrenSchool of Medicine and Health Sciences, Psychiatry and Psychotherapy, University Hospital Karl-Jaspers-Klinik, University of Oldenburg, Oldenburg, Germany.
Jale ÖzyurtBiological Psychology Lab, Department of Psychology, European Medical School, University of Oldenburg, Oldenburg, Germany.
Alexandra P LamDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
Mirko BrandesUnit Applied Health Intervention Research, Department of Prevention and Evaluation, Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH, Bremen, Germany.
Helge H O MüllerDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
Christiane M ThielBiological Psychology Lab, Department of Psychology, European Medical School, University of Oldenburg, Oldenburg, Germany.
Alexandra PhilipsenDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
University of Bonn · DECarl von Ossietzky Universität Oldenburg · DEHearing4all · DELeibniz Institute for Prevention Research and Epidemiology - BIPS · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aerobic exercise can improve cognitive functions in healthy individuals and in various clinical groups, which might be particularly relevant for patients with ADHD. This study investigated the effects of a single bout of aerobic exercise on attention and executive functions in adult patients with ADHD, including functional MRI to examine the underlying neural mechanisms. On two different days, 23 adult patients with ADHD and 23 matched healthy controls performed in a flanker task, while functional MR images were collected, following 30 min of continuous stationary cycling with moderate intensity as well as after a control condition (watching a movie). Behavioral performance and brain activation were tested for differences between groups and conditions and for interactions to investigate whether exercise improves executive function to a greater extent in patients compared to healthy controls. Exercise significantly improved reaction times in congruent and incongruent trials of the flanker task in patients with ADHD but not in healthy controls. We found no changes in brain activation between the two conditions for either group. However, a subgroup analysis of ADHD patients with a higher degree of cardiorespiratory fitness revealed decreased activation in premotor areas during congruent trials and in premotor and medial frontal cortex during incongruent trials in the exercise compared to the control condition. Our results indicate exercise-induced improvements in attention and processing speed in patients with ADHD, demonstrating that adult patients with ADHD may benefit from an acute bout of exercise. These findings could be of high relevance for developing alternative treatment approaches for ADHD. In addition, results of the current study contribute to elucidate the neurophysiological mechanisms underlying the beneficial effects of exercise on cognition and to better understand the role of cardiorespiratory fitness on these effects.

Indexed as

acute aerobic exerciseadult ADHDbrain activationcardiorespiratory fitnesscognitionexecutive functionfMRIphysical activity

Identifiers

PMID30971959
PMCPMC6443849
OpenAlexW2922910775

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.