ArticleScientific reports2019
Hippocampal and cortical communication around micro-arousals in slow-wave sleep.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Refined Division of Sleep Stages in the Mouse Based on Distributed Deep Electrodes and Underlying Infra-Slow Oscillation.Journal of sleep research · 2026Article
- Cortical firing dynamics during micro-arousals vary with sleep/wake history and micro-arousal duration.Scientific reports · 2026Article
- Entrained cortical delta-spindle activity, not periodic synchrony, prevents arousal by NREM thalamic bursts.Communications biology · 2026Article
- First night effect alters occipital brain connectivity in horses.Scientific reports · 2025Article
- Ultraslow serotonin oscillations in the hippocampus delineate substates across NREM and waking.eLife · 2025Article
- Modulation of Hippocampal Sharp-Wave Ripples by Behavioral States and Body Movements in Head-Fixed Rodents.eNeuro · 2025Article
- Article
- Novel murine closed-loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration.Journal of sleep research · 2025Article
- Serotonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep.bioRxiv : the preprint server for biology · 2025Article
- Sleep-stage dependent patterning of slowly propagating brain activity.Npj biological timing and sleep · 2025Article
- Noradrenaline Regulation of Brain-Body Communication.Advances in experimental medicine and biology · 2025Review
- Functional connectivity drifts during sleep as a marker of fluctuations in the level of consciousness.Neuroscience of consciousness · 2025Article
- Circuit mechanism underlying fragmented sleep and memory deficits in 16p11.2 deletion mouse model of autism.iScience · 2024Article
- Thermal effects and ephaptic entrainment in Hodgkin-Huxley model.Scientific reports · 2024Article
- Role of the Locus Coeruleus Arousal Promoting Neurons in Maintaining Brain Criticality across the Sleep-Wake Cycle.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Circuit mechanism underlying fragmented sleep and memory deficits in 16p11.2 deletion mouse model of autism.bioRxiv : the preprint server for biology · 2024Article
- Sleep restores an optimal computational regime in cortical networks.Nature neuroscience · 2024Article
- Article
- Regulation of stress-induced sleep fragmentation by preoptic glutamatergic neurons.Current biology : CB · 2024Article
- Somnotate: A probabilistic sleep stage classifier for studying vigilance state transitions.PLoS computational biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Sleep plays a crucial role in the regulation of body homeostasis and rhythmicity in mammals. Recently, a specific component of the sleep structure has been proposed as part of its homeostatic mechanism, named micro-arousal. Here, we studied the unique progression of the dynamic behavior of cortical and hippocampal local field potentials (LFPs) during slow-wave sleep-related to motor-bursts (micro-arousals) in mice. Our main results comprised: (i) an abrupt drop in hippocampal LFP amplitude preceding micro-arousals which persisted until the end of motor-bursts (we defined as t interval, around 4s) and a similar, but delayed amplitude reduction in cortical (S1/M1) LFP activity occurring at micro-arousal onset; (ii) two abrupt frequency jumps in hippocampal LFP activity: from Theta (6-12 Hz) to Delta (2-4 Hz), also t seconds before the micro-arousal onset, and followed by another frequency jump from Delta to Theta range (5-7 Hz), now occurring at micro-arousal onset; (iii) a pattern of cortico-hippocampal frequency communication precedes micro-arousals: the analysis between hippocampal and cortical LFP fluctuations reveal high coherence during τ interval in a broader frequency band (2-12 Hz), while at a lower frequency band (0.5-2 Hz) the coherence reaches its maximum after the onset of micro-arousals. In conclusion, these novel findings indicate that oscillatory dynamics pattern of cortical and hippocampal LFPs preceding micro-arousals could be part of the regulatory processes in sleep architecture.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.