Evidence map›Paper›PMID 30971749›Full record

ArticleScientific reports2019

Effects of exogenous melatonin on clinical and pathological features of a human thyroglobulin-induced experimental autoimmune thyroiditis mouse model.

Jiunn-Diann Lin, Wen-Fang Fang, Kam-Tsun Tang, Chao-Wen Cheng

Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07650552 (Effect of the Association of Fentanyl and Rocuronium on First-Attempt Success Rate of Tracheal Intubation in Newborns), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07650552 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of the Association of Fentanyl and Rocuronium on First-Attempt Success Rate of Tracheal Intubation in Newborns: A Randomized Clinical Trial

TypeinterventionalSponsorUEA - Universidade Do Estado Do AmazonasRan2026 to 2029Enrolled102ConditionsInfant, Premature, Intubation, Intratracheal, Respiratory Distress Syndrome, Newborn, Apnea of PrematurityArmsRocuronium Bromide 10 MG/ML, Fentanyl 1 mcg/kg IV, single dose, administered before non-emergent tracheal intubation.
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Association ofInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Experimental rat models for Hashimoto's thyroiditis.Journal of endocrinological investigation · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jiunn-Diann LinGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Wen-Fang FangDepartment of Family Medicine, Shuang Ho Hospital, New Taipei City, Taiwan.
Kam-Tsun TangDivision of Endocrinology and Metabolism, Department of Internal Medicine, Veterans General Hospital, Taipei, Taiwan.
Chao-Wen ChengGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. ccheng@tmu.edu.tw.
Taipei Medical University · TWTaipei Medical University-Shuang Ho Hospital · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melatonin (MLT) plays a significant role in both innate and adaptive immunity, and dysregulation of the MLT signature can modify autoimmune disease phenotypes. In this study, the influence of exogenous MLT administration on regulating autoimmune thyroiditis animal models was evaluated. An experimental autoimmune thyroiditis model was established in MLT-synthesizing (CBA) and MLT-deficient (C57BL/6) mice by immunization with human thyroidglobulin (TG), which features thyrotoxicosis, thyrocyte damage, and CD3

Indexed as

AnimalsAutoantibodiesCell ProliferationDisease Models, AnimalFemaleHumansMelatoninMiceMice, Inbred C57BLMice, Inbred CBASpleenThyroglobulinThyroid GlandThyroiditis, AutoimmuneThyroxineT-Lymphocytesanti-thyroglobulinAutoantibodiesMelatoninThyroglobulinThyroxineTriiodothyronine

Identifiers

PMID30971749
PMCPMC6458129
OpenAlexW2938392996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.