Evidence map›Paper›PMID 30971414›Full record

ArticleThe Journal of cell biology2019

Peroxisome protein import recapitulated in

Fabian B Romano, Neil B Blok, Tom A Rapoport

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. PEX1The Journal of biological chemistry · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fabian B RomanoHoward Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, Boston, MA.ORCID 0000-0002-2263-4317
Neil B BlokHoward Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, Boston, MA.
Tom A RapoportHoward Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, Boston, MA tom_rapoport@hms.harvard.edu.ORCID 0000-0001-9911-4216
Howard Hughes Medical Institute · US

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
NIGMS NIH HHS T32 GM007753
6 · The paper itself

Abstract

Peroxisomes import their luminal proteins from the cytosol. Most substrates contain a C-terminal Ser-Lys-Leu (SKL) sequence that is recognized by the receptor Pex5. Pex5 binds to peroxisomes via a docking complex containing Pex14, and recycles back into the cytosol following its mono-ubiquitination at a conserved Cys residue. The mechanism of peroxisome protein import remains incompletely understood. Here, we developed an in vitro import system based on

Indexed as

AnimalsCell ExtractsCytosolFemaleOocytesPeroxisomesPeroxisome-Targeting Signal 1 ReceptorProtein TransportUbiquitinationXenopus laevisXenopus ProteinsCell ExtractsPeroxisome-Targeting Signal 1 ReceptorXenopus Proteins

Identifiers

PMID30971414
PMCPMC6548129
OpenAlexW2937704628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.