Evidence map›Paper›PMID 30971410›Full record

ArticleBiology open2019

Quantitative analysis of the ThrbCRM1-centered gene regulatory network.

Benjamin Souferi, Mark M Emerson

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Benjamin SouferiDepartment of Biology, The City College of New York, City University of New York, New York, NY 10031, USA.
Mark M EmersonDepartment of Biology, The City College of New York, City University of New York, New York, NY 10031, USA memerson@ccny.cuny.edu.ORCID http://orcid.org/0000-0002-1914-5782
City College of New York · USThe Graduate Center, CUNY · US

Funding

Cellular/Molecular Basis of Development: Research CenterG12MD007603 · NIMHD · CITY COLLEGE OF NEW YORK · PI PEZZANO, MARK · 2012 to 2017
$11.5M
Transcriptional Regulation of Cone Photoreceptor GenesisR01EY024982 · NEI · CITY COLLEGE OF NEW YORK · PI EMERSON, MARK M · 2015 to 2023
$3.2M
NEI NIH HHS R01 EY024982NIMHD NIH HHS G12 MD007603
6 · The paper itself

Abstract

Enhancer activity is determined by both the activity and occupancy of transcription factors as well as the specific sequences they bind. Experimental investigation of this dynamic requires the ability to manipulate components of the system, ideally in as close to an

Indexed as

Cis-regulatory elementsCone photoreceptorsElectroporationFlow cytometryGene regulatory networksQuantitative analysisReporter assaysRetinal development

Identifiers

PMID30971410
PMCPMC6504004
OpenAlexW2913861879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.