ArticleG3 (Bethesda, Md.)2019
The Effect of Neutral Recombination Variation on Genome Scans for Selection.
Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 84 citations in OpenAlex.
- Range-Wide Genetic Population Structure and Environmental Adaptation in the Eastern Oyster (Crassostrea virginica) Provides Insight for Aquaculture.Molecular ecology · 2026Article
- Genome-Wide Population Structure of Lake Whitefish (Evolutionary applications · 2026Article
- Conservation Units for Anadromous Arctic Char (Evolutionary applications · 2026Article
- Replicated hybrid zones reveal genomic patterns of local adaptation and introgression in spruce.Molecular biology and evolution · 2026Article
- Admixture Increases Genetic Diversity and Adaptive Potential in Australasian Killer Whales.Molecular ecology · 2025Article
- Identifying the Degree of Gene Reuse During Repeated Adaptation.Molecular ecology · 2025Review
- De novo genome assembly, inversion detection, and worldwide adaptation on the invasive species Styela plicata.Scientific reports · 2025Article
- Effects of using deep learning to predict the geographic origin of barley genebank accessions on genome-environment association studies.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Discovery of major QTL and a massive haplotype associated with cannabinoid biosynthesis in drug-type Cannabis.The plant genome · 2025Article
- Genetic Differentiation is Constrained to Chromosomal Inversions and Putative Centromeres in Locally Adapted Populations With Higher Gene Flow.Molecular biology and evolution · 2025Article
- Resource-explicit interactions in spatial population models.Methods in ecology and evolution · 2024Article
- Genetics in the Ocean's Twilight Zone: Population Structure of the Glacier Lanternfish Across Its Distribution Range.Evolutionary applications · 2024Article
- Consequences of domestication in eastern oyster: Insights from whole genomic analyses.Evolutionary applications · 2024Article
- Current status of community resources and priorities for weed genomics research.Genome biology · 2024Review
- Versatile Detection of Diverse Selective Sweeps with Flex-Sweep.Molecular biology and evolution · 2023Article
- The paradox of adaptive trait clines with nonclinal patterns in the underlying genes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Development and Evaluation of High-Density SNP Arrays for the Eastern Oyster Crassostrea virginica.Marine biotechnology (New York, N.Y.) · 2023Article
- High-density genomic data reveal fine-scale population structure and pronounced islands of adaptive divergence in lake whitefish (Evolutionary applications · 2022Article
- Genomic differentiation in Pacific cod using Pool-Seq.Evolutionary applications · 2022Article
- Simulation Tests of Methods in Evolution, Ecology, and Systematics: Pitfalls, Progress, and Principles.Annual review of ecology, evolution, and systematics · 2022Article
Corrections and comments
- Erratum issuedCorrigendum.2019
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, there has been an increasing interest in identifying the role that regions of low recombination or inversion play in adaptation of species to local environments. Many examples of groups of adapted genes located within inversions are arising in the literature, in part inspired by theory that predicts the evolution of these so-called "supergenes." We still, however, have a poor understanding of how genomic heterogeneity, such as varying rates of recombination, may confound signals of selection. Here, I evaluate the effect of neutral inversions and recombination variation on genome scans for selection, including tests for selective sweeps, differentiation outlier tests, and association tests. There is considerable variation among methods in their performance, with some methods being unaffected and some showing elevated false positive signals within a neutral inversion or region of low recombination. In some cases the false positive signal can be dampened or removed, if it is possible to use a quasi-independent set of SNPs to parameterize the model before performing the test. These results will be helpful to those seeking to understand the importance of regions of low recombination in adaptation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.