Evidence map›Paper›PMID 30971281›Full record

ArticleJournal of cardiothoracic surgery2019

Failed MitraClip therapy: surgical revision in high-risk patients.

Sabreen Mkalaluh, Marcin Szczechowicz, Matthias Karck, Alexander Weymann

Abstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Mitral valve surgery after a failed MitraClip procedure.Interactive cardiovascular and thoracic surgery · 2021
    Pooled it
  2. Article
  3. Review
  4. On site cardiac surgery for structural heart interventions: a fence to mend?European heart journal supplements : journal of the European Society of Cardiology · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sabreen MkalaluhDepartment of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. sabreen.mkalaluh@gmx.de.
Marcin SzczechowiczDepartment of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Matthias KarckDepartment of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Alexander WeymannDepartment of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMitraClip implantation is a valid interventional option that offers acceptable short-term results. Surgery after failed MitraClip procedures remains challenging in high-risk patients. The data on these cases are limited by the small sample numbers.

aimThe aim of our study is to show, that mitral valve surgery could be possible and more advantageous, even in high-risk patients.

methodsBetween 2010 and 2016, nine patients underwent mitral valve surgery after failed MitraClip therapy at our institution.

resultsThe patients' ages ranged from 19 to 75 years (mean: 61.2 ± 19.6 years). The median interval between the MitraClip intervention and surgical revision was 45 days (range: 0 to 1087 days). In eight of nine patients, the MitraClip intervention was initially successful and the  mitral regurgitation was reduced. Only one patient had undergone cardiac surgery previously. Intra-operatively, leaflet perforation or rupture, MitraClip detachment, and chordal or papillary muscle rupture were potentially the causes of recurrent mitral regurgitation. There were three early deaths. One year after surgery, the six remaining patients were alive.

conclusionsMitral valve surgery can be successfully performed after failed MitraClip therapy in high-risk patients. The initial indication for MitraClip therapy should be considered carefully for possible surgical repair.

Indexed as

Equipment FailureAdultAgedFemaleHeart Valve Prosthesis ImplantationHumansIntraoperative ComplicationsMaleMiddle AgedMitral ValveMitral Valve InsufficiencyRecurrenceReoperationTime FactorsTreatment OutcomeYoung AdultMitraClip therapyMitral regurgitationOutcomeShort-term survivalSurgical therapy

Identifiers

PMID30971281
PMCPMC6458691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.