ArticlePolymers2017
Are There Knots in Chromosomes?
Article in Polymers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Topology-Based Detection and Tracking of Deadlocks Reveal Aging of Active Ring Melts.ACS macro letters · 2024Article
- Geometric learning of knot topology.Soft matter · 2023Article
- Homology of homologous knotted proteins.Journal of the Royal Society, Interface · 2023Article
- Reconstructing diploid 3D chromatin structures from single cell Hi-C data with a polymer-based approach.Frontiers in bioinformatics · 2023Article
- Geometric Predictors of Knotted and Linked Arcs.ACS polymers Au · 2022Article
- Modeling cell biological features of meiotic chromosome pairing to study interlock resolution.PLoS computational biology · 2022Article
- Influence of ionic conditions on knotting in a coarse-grained model for DNA.Frontiers in chemistry · 2022Article
- DNA-Topology Simplification by Topoisomerases.Molecules (Basel, Switzerland) · 2021Review
- Topoly: Python package to analyze topology of polymers.Briefings in bioinformatics · 2021Article
- Polymer modelling unveils the roles of heterochromatin and nucleolar organizing regions in shaping 3D genome organization in Arabidopsis thaliana.Nucleic acids research · 2021Article
- Condensin minimizes topoisomerase II-mediated entanglements of DNA in vivo.The EMBO journal · 2021Article
- Chromatin Is Frequently Unknotted at the Megabase Scale.Biophysical journal · 2020Article
- Grid diagrams as tools to investigate knot spaces and topoisomerase-mediated simplification of DNA topology.Science advances · 2020Article
- Active topological glass.Nature communications · 2020Article
- Defining and detecting links in chromosomes.Scientific reports · 2019Article
- The Rabl configuration limits topological entanglement of chromosomes in budding yeast.Scientific reports · 2019Article
- Topological Constraints in Eukaryotic Genomes and How They Can Be Exploited to Improve Spatial Models of Chromosomes.Frontiers in molecular biosciences · 2019Article
- Chromatin Loop Extrusion and Chromatin Unknotting.Polymers · 2018Article
- KnotGenome: a server to analyze entanglements of chromosomes.Nucleic acids research · 2018Article
- Article
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6 authors.
Funding
Abstract
Recent developments have for the first time allowed the determination of three-dimensional structures of individual chromosomes and genomes in nuclei of single haploid mouse embryonic stem (ES) cells based on Hi⁻C chromosome conformation contact data. Although these first structures have a relatively low resolution, they provide the first experimental data that can be used to study chromosome and intact genome folding. Here we further analyze these structures and provide the first evidence that G1 phase chromosomes are knotted, consistent with the fact that plots of contact probability vs sequence separation show a power law dependence that is intermediate between that of a fractal globule and an equilibrium structure.
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