ArticlePolymers2017
Electrospun Polycaprolactone/Aloe Vera_Chitosan Nanofibrous Asymmetric Membranes Aimed for Wound Healing Applications.
Article in Polymers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed.
- Smart Nanofibers in Wound Healing: Exploring Novel Combinations and Applications.Current drug delivery · 2026Review
- Performance study of ZnO-TPU/CS bilayer composite electrospinning scaffold in skin wound healing.Frontiers in bioengineering and biotechnology · 2025Article
- Titanium dioxide nanoparticles: a promising candidate for wound healing applications.Burns & trauma · 2025Review
- Article
- Electrospun Poly-ε-Caprolactone Nanofibers Incorporating Keratin Hydrolysates as Innovative Antioxidant Scaffolds.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Cerium oxide nanoparticles: Synthesis methods and applications in wound healing.Materials today. Bio · 2023Review
- Regulating AlNanomaterials (Basel, Switzerland) · 2023Article
- Multi-material electrospinning: from methods to biomedical applications.Materials today. Bio · 2023Review
- Review
- Recent Tissue Engineering Approaches to Mimicking the Extracellular Matrix Structure for Skin Regeneration.Biomimetics (Basel, Switzerland) · 2023Review
- Nanofibrous Scaffolds for Diabetic Wound Healing.Pharmaceutics · 2023Review
- Effect of PCL nanofiber mats coated with chitosan microcapsules containing cinnamon essential oil for wound healing.BMC complementary medicine and therapies · 2023Article
- Fabrication of a Polycaprolactone/Chitosan Nanofibrous Scaffold Loaded withBiotech (Basel (Switzerland)) · 2023Article
- Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review.Frontiers in chemistry · 2023Review
- Synthesis and Characterization of PU/PLCL/CMCS Electrospun Scaffolds for Skin Tissue Engineering.Polymers · 2022Article
- Article
- Electrospun Polymer Nanofibers with Antimicrobial Activity.Polymers · 2022Review
- Research progress, models and simulation of electrospinning technology: a review.Journal of materials science · 2022Review
- Preliminary Characterization of a Polycaprolactone-SurgihoneyRO Electrospun Mesh for Skin Tissue Engineering.Materials (Basel, Switzerland) · 2021Article
- Understanding and utilizing textile-based electrostatic flocking for biomedical applications.Applied physics reviews · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Today, none of the wound dressings available on the market is fully capable of reproducing all the features of native skin. Herein, an asymmetric electrospun membrane was produced to mimic both layers of skin. It comprises a top dense layer (manufactured with polycaprolactone) that was designed to provide mechanical support to the wound and a bottom porous layer (composed of chitosan and Aloe Vera) aimed to improve the bactericidal activity of the membrane and ultimately the healing process. The results obtained revealed that the produced asymmetric membranes displayed a porosity, wettability, as well as mechanical properties similar to those presented by the native skin. Fibroblast cells were able to adhere, spread, and proliferate on the surface of the membranes and the intrinsic structure of the two layers of the membrane is capable of avoiding the invasion of microorganisms while conferring bioactive properties. Such data reveals the potential of these asymmetric membranes, in the near future, to be applied as wound dressings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.